Sentences with phrase «associated systemic disease»

Not exact matches

Investigators at the Medical University of South Carolina (MUSC) report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome, in the January 2017 issue of Nature Genetics.

Lastly, increased systemic inflammation seen during ageing is also apparent in chronic infections such HIV or cytomegalovirus, 10,15 obesity7 and individuals enduring chronic psychological stress.16 Similarly, the main features of immunosenescence are apparent in many of these conditions, including decreased antibody responses, increased infections, malignancies and also incidences of inflammatory associated disorders such as cardiovascular disease.7, 10,15,16 Inflammation and premature immunosenescence are, therefore, prevalent features of many common conditions of modern life, such as obesity and stress, and could have negative health consequences for large proportions of society well before old age is reached.

The ITN will prioritize studies in a few selected autoimmune diseases, building on previous experience (e.g., systemic lupus erythematosus, ANCA - associated vasculitis, psoriasis, multiple sclerosis), prioritizing diseases with a relevant antigen (whether self or microbial in origin) that can be targeted and monitored (e.g., pemphigus, MS, ANCA - associated vasculitis), and / or diseases with accessible tissue (e.g., psoriasis, inflammatory bowel disease, pemphigus, scleroderma).

This is not natural, and over time, this chronic inflammation is associated with many diseases — from the painful inflammation of arthritis to the systemic inflammation of heart disease to the insidious variety that's associated with brain fog, fatigue, and weight gain.

Macmillan, 2014; Holler, E., et al. «Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft - versus - host disease.»

The consequences of this systemic inflammation are most of the diseases and conditions associated with the Western lifestyle:

It is also associated with systemic inflammation and indices of physical frailty in aging (17) and is particularly elevated in those with celiac disease (6).

The end result of these two mechanisms is that much more of the statin drug enters the systemic circulation than would normally be the case, leading to a build up in statin levels that can be quite dangerous, and may trigger a rare but serious statin - associated disease called rhabdomyolysis.

A connective tissue disease, systemic sclerosis, has also been associated with hypothyroidism.

It was found to be associated with multiple autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, type 1 diabetes, Graves» disease and Hashimoto's thyroiditis.

The gene was found to be associated with a variety of autoimmune conditions such as type 1 diabetes, asthma, Addison's disease, myasthenia gravis, Sjorgren's syndrome, systemic lupus erythematosus (SLE), systemic sclerosis, ulcerative colitis and all forms of AITD including Grave's disease and Hashimoto's thyroiditis.

In a study published by the National Institutes of Health, «TFA (Trans Fatty Acid) intake is positively associated with markers of systemic inflammation... (the) influences of TFAs on inflammation and of implications for coronary disease, diabetes, and other conditions is warranted.»

I have read that H. pylori is associated with a wide variety of health problems, but are you aware of cases where H. pylori seemed to be the primary cause of major systemic (as opposed to narrowly gastric) disease, which then resolved upon treatment of H. pylori?

We excluded trials concerning calcium and vitamin D given together with a placebo comparator (trials were only eligible if vitamin D was given to both intervention and control groups, because vitamin D supplementation has been associated with decreased mortality17); trials in which calcium was administered in the form of dietary modification or a complex nutritional supplement; and trials in which most participants had a major systemic disease other than osteoporosis.

Often, an associated underlying immunosuppressive disease, such as FIV, FeLV, diabetes mellitus, hyperadrenocorticism, toxoplasmosis, systemic lupus erythematosus, or squamous cell carcinoma in situ is present in patients with generalized disease.3

Chronic diarrhea can be associated with certain parasites, food allergies, inflammatory bowel disease, pancreatic disorders, and systemic conditions such as hyperthyroidism.

Other systemic diseases may also manifest as abnormalities in the eyes — inflammation or bleeding in the eye may be associated with inflammation or bleeding in other areas in the body, respectively.

Just as oral health is important for excellent health in humans, dogs too, require a healthy oral cavity and teeth so they will be adequately protected from a variety of systemic diseases associated with canine periodontal disease.

Clinical improvement of signs associated with systemic illness and pain is expected in the first week of antibiotic therapy.3 It is important that patients return for follow - up neurologic exams and radiography every 1 to 2 months to monitor for disease progression and to help direct therapy.

An adult - onset disease is considered rare, and when it does occur, usually is a result of compromised immunity associated with other systemic diseases like Cushing's disease or cancer.

Although greater early local production of proinflammatory cytokines at wound sites is beneficial because it is associated with enhanced healing, greater systemic production of proinflammatory cytokines can represent a maladaptive response.24 Both physical and psychological stressors can provoke transient increases in plasma levels of proinflammatory cytokines, particularly IL - 6,25 as can negative emotions like depression and anxiety.26 - 28 More frequent or persistent stress - related changes have broad implications for physical and mental health; sustained elevated levels of proinflammatory cytokines have been linked to a variety of age - related diseases, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 - 31