Sentences with phrase «atypical development in»

«Predicting atypical development in infants at high risk for autism?.»

New research from the Sackler Institute for Developmental Psychobiology at Columbia University Medical Center (CUMC) identifies a potential biomarker that predicts atypical development in 1 - to 2 - month - old infants at high versus low familial risk for developing autism spectrum disorders (ASD).

«Atypical development in siblings of children with autism is detectable at 12 months.»

Not exact matches

The historic ferment and developments in modern Catholic thought are dismissed (if anything is known about them) as atypical or even hypocritical.

Atypical brain activation to speech in infants with inherited risk for dyslexia impedes the development of effective connections to the mental lexicon, and thus slows the naming and reading performances.

Can this atypical system of stellar rotation observed in MACS2129 - 1 be interpreted as a form of «prototype» representing an early stage in the development of elliptic - shaped galaxies?

Although the mechanism behind the association remains a mystery, the findings may have implications for minimizing risks of atypical brain development in children.

Lead author Masahiro Imafuku adds that a lack of interest in social stimuli — for instance, another person — could be an early sign for whether preterm infants are following a path toward atypical social development.

However, alcohol - exposed children did not show this pattern, possibly due to atypical or delayed brain development, which has been observed in other research studies.

We're looking into whether the shrill cries correlate with atypical cognitive development in infancy.»

These and other insights from developmental cognitive neuroscience can and should inform theories of atypical development of functional connectivity in autism.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.in AML and breast cancer patients.10

«Atypical development of local and distant intrinsic functional connectivity in ASD,» in Paper Presented at the Organization for Human Brain Mapping, (Beijing).

Gaab also theorizes that children who are born susceptible to dyslexia have atypical brain development in the left hemisphere, which makes it difficult for them to develop components of the language and reading network there.

Her current research within the Laboratories of Cognitive Neuroscience focuses on auditory and language processing in the human brain and its applications for the development of typical and atypical language and literacy skills.

Impact of orthographic transparency on typical and atypical reading development: evidence in French - Spanish bilingual children.

Areas of professional development addressing how a student's cultural background may influence behavior, the typical and atypical language and literacy characteristics of English learner students, or how best to communicate and interact with parents can all aid in improving teacher understanding, according to the study.

An internationally renowned expert in the field of gender - based biology, he has identified a large number of mutations in sex - determining genes, developed animal models with atypical sexual development, and identified novel mechanisms of sex differences in the brain.

, Emotional Development in Atypical Children (pp. 109 - 130).

Join a free webinar with Dr. Elaine Schulte to learn how to differentiate between typical and atypical development and behavior in children, specifically as it relates to adopted children.

Expression and Understanding of Emotion in Atypical Development: Autism and Down Syndrome.

• Knowledge in program planning and case management for children with special needs, including knowledge of atypical development.

Summarizing the empirical evidence, Barnett and colleagues [75] suggested a two - dimensional model in which both biological vulnerability as well as adverse environment might contribute to the development of atypical (disorganised) attachment behaviour.

In the current study, we tested whether atypical structural development in several areas of the brain tied to school readiness skills may have mediated the relationship between childhood poverty and impaired academic performancIn the current study, we tested whether atypical structural development in several areas of the brain tied to school readiness skills may have mediated the relationship between childhood poverty and impaired academic performancin several areas of the brain tied to school readiness skills may have mediated the relationship between childhood poverty and impaired academic performance.

This branch concentrates on atypical development and maladaptive outcomes in comparison with normal development.

There is a strong need to change the perception of the early childhood field towards first and most valuable point of interaction and intervention for children typical and atypical in development.

Dissociation in typical and atypical development: Examples from father - daughter incest survivors.

• Knowledgeable about early development (pregnancy - delivery and first 3 years of life), typical and atypical development and in multiple domains.

• to describe the lives of children in Ireland, in order to establish what is typical and normal as well as what is atypical and problematic; • to chart the development of children over time, in order to examine the progress and wellbeing of children at critical periods from birth to adulthood; • to identify the key factors that, independently of others, most help or hinder children's development; • to establish the effects of early childhood experiences on later life; • to map dimensions of variation in children's lives; • to identify the persistent adverse effects that lead to social disadvantage and exclusion, educational difficulties, ill health and deprivation; • to obtain children's views and opinions on their lives; • to provide a bank of data on the whole child; and to provide evidence for the creation of effective and responsive policies and services for children and families; • to provide evidence for the creation of effective and responsive policies and services for children and families.

Martin's expertise is in early childhood special education, differentiated instruction in inclusive classrooms, autism spectrum disorders, and typical and atypical social and emotional development.

[jounal] Lyons - Ruth, K. / 1999 / Maternal frightened, frightening, or atypical behavior and disorganized infant attachment patterns / Monographs of the Society for Research in Child Development 64: 67 ~ 96

In line with previous research on the disadvantage of the incongruence of prenatal and postnatal environments on early child development [25], we hypothesized that children whose mothers had elevated postnatal maternal depressive symptoms when compared to that during pregnancy may show greater atypical frontal EEG activity and frontal functional connectivity and greater internalizing and externalizing behavioral problems.

Additionally, the ASD group reported high levels of separation anxiety and panic in late adolescence, possibly indicating atypical development of independence.