Sentences with phrase «autologous cd4»
IFN - α Augments NK - mediated Antibody - Dependent Cellular Cytotoxicity (ADCC) of HIV - 1 Infected Autologous CD4 + T Cells Regardless of MHC - I Downregulation.
http://beat-hiv.org/
On day 28 post-engraftment, mice were intravenously injected with 105 autologous CD4 + T cells that were previously infected with the highly cytopathic X4 HIV - 1 strain Bk132 or a mock control.
To infect the mice with HIV - 1, 105 autologous CD4 + T cells previously infected with X4 HIV - 1 strain Bk132 were injected into the tail vein of each mouse.
Not exact matches
Several early stage clinical trials using autologous infusions of ZFN - generated CCR5 - modified CD4 + T cells are currently underway (clinicaltrials.gov identifiers NCT00842634, NCT01252641, NCT01044654).
In addition, transgenic autologous hematopoietic stem cells can be successfully transplanted in HIV - infected individuals [18] and several phase I adoptive transfer trials of CD4 + T cells treated with R5 - ZFNs in HIV infected individuals are currently underway.
However, coreceptor - specific ZFNs represent a novel therapeutic approach to recapitulate this success via autologous transplantation of gene - modified hematopoietic stem cells and mature CD4 + T cells.