As a part of VIOLIN, we have developed Vaxign, the first web - based publically
available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
A key program of VIOLIN is Vaxign, the first web - based publically
available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
Not exact matches
Previous infection with one serotype of dengue, or protection against just one serotype, can lead to more severe disease if a person contracts other serotypes, so it's vital that
vaccines are
available that specifically
target all four strains.
There is no licensed
vaccine available to treat or prevent dengue fever, and efforts to develop one have been complicated by the fact that dengue is caused by four distinct dengue viruses, and a
vaccine must
target all four serotypes (DENV 1 - 4).
Broadly neutralizing antibodies (bNAbs), if elicited by a
vaccine, could prevent infection by a broad range of HIV's many variants, and the Envelope protein is the sole
target available to these antibodies.
It is now predicting a 70 percent likelihood that there will not be enough H1N1
vaccine available to hit government
targets until at least December, and a a more than 90 percent probability that more than half of U.S. flu cases this season will be swine flu.