Sentences with phrase «b cell application»
Further development of the B cell application therapy may lead to novel ways of addressing the pathologies underlying the formation of chronic wounds.»
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Their series of experiments showed that a single application of concentrated, mature B cells accelerated wound healing and improved the quality of tissue repair in both animal models.
«Mature B lymphocytes accelerate the healing of diabetic ulcers, other skin injuries: Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models.»
Among other applications, its innovative technological platform enables identifying and analyzing the genetic diversity of B cells to convert them into polyclonal recombinant antibodies (biotherapeutics) that improve outcomes for patients with severe diseases.
NEMO / IKK: Targeting the interaction between NEMO and IKK to block pathological NF - kB signaling has many therapeutic applications in inflammatory and autoimmune diseases (RA, IBD, psoriasis, acute inflammatory indications, etc.) and oncology (immuno - oncology, B - cell lymphomas, and solid tumors).
<b> Results b>: The application of specific optimised conditions induce multiple rounds of memory B cell proliferation equally across Ig isotypes, differentiation of memory B cells to antibody secreting cells, and importantly do not alter the Ig genotype of the stimulated cells.
Current research applications focus on new approaches to a) drug and probe development for neurodegenerative disorders and diseases including Schizophrenia, Alzheimer's, and Parkinson's, b) understanding the structural determinants of antidepressant binding to neurotransmitter transporters, c) cardiac arrhythmia as caused by the complex interplay of potassium channel regulation and drug interactions, d) multidrug resistance in cancer and bacterial cells related to multidrug transporter proteins, and e) structural basis of viral infections and antibody activity.