Sentences with phrase «b cell biology»
Given that many recent studies of B cell biology take advantage of Ig - transgenic (or knockin equivalent) mice for their entire analysis, we do not feel that our use of the approach as one part of the present study is out of line with currently accepted practice in the field.
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«Research focused on basic B cell biology is the foundation for the development of an HIV vaccine designed to drive the B cell arm of the immune response.»
To address the contribution of the GARP: TGF - beta axis to B cell biology, the Li lab generated two preclinical models: one in which GARP was overexpressed and one in which GARP expression was reduced.
Not exact matches
 Much of transplant biology focuses on one type of immune cell (T cells), but Newell found that the cells that may make the biggest difference for long - term tolerance are different, B cells.
DGKζ, a lipid kinase, phosphorylates the second messenger DAG, terminating DAG - mediated activation of RasGRP1 and PKC - θ, whereas Cbl - b, an E3 ubiquitin ligase, facilitates ubiquitination and subsequent degradation of the p85 subunit of PI (3) K. Previous studies have evaluated numerous aspects of T cell biology in the two models (16 — 18, 25, 38), but the signaling and functional effects of DKGζ deficiency and Cbl - b deficiency in T cells had not been directly compared.
Indeed, RIPK2 inhibitors 1 and 2 did not inhibit RIPK1 biology nor ferroptosis, a form of cell death influenced by proteins of the RIPK family (Supplemental Fig. 6, A and B).
«It was the first time I had ever received a grade lower than a B, and it was upsetting,» admits Mercado, a biochemistry and cell biology major at the University of California, San Diego.
After graduating from UC San Diego with a BS in cell biology / biochemistry in 1992, she attended UC Davis and earned her doctor of veterinary medicine (DVM) in 1996.