Sentences with phrase «bub1b gene encodes a protein»

The gene encodes a protein that is important for intracellular transportation.

No. 5,817,479, entitled Human Kinase Homologs, claims 44 ESTs which are fragments of genes encoding protein kinases.

The gene encodes a protein called PD - 1 that normally acts as a check on the cell's capacity to launch an immune response, to prevent it from attacking healthy cells.

«This gene encodes a protein which recognises the presence of a certain number of cold - inducing microbes in a cell, such as the respiratory syncytial virus (RSV) or rhinoviruses,» explains Samira Asgari of EPFL, who designed the experiments.

Mutations in the genes encoding proteins that regulate cohesin and cohesin protein itself cause the developmental disorder Cornelia de Lange syndrome (CdLS).

PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.

Normal BRCA genes encode proteins that are cancer suppressors.

This gene encodes a protein that plays a well - known role in regulating the body's immune response to infection.

New discoveries about the rules governing how genes encode proteins have revealed nature's sophisticated «programming» for protecting life from catastrophic errors while accelerating evolution

She and her colleagues found that expression of a variety of genes encoding proteins related to collagen and extracellular matrix, was reduced.

This gene encodes a protein that regulates gene expression, producing a new mutant that gives the seed new properties.

Since the successful sequencing of the human genome, interest in the group of genes encoding proteins responsible for DNA remodeling has grown exponentially.

That means a healthy parent whose huntingtin gene encodes proteins with 35 repeats may produce a child with 36 repeats.

In its healthy form the gene encodes a protein that unwinds DNA, presumably so other proteins that manipulate DNA can wriggle between the strands to do their work.

If the gene encoding a protein is duplicated in the genome, which often happens in evolution, original and copy will interact with the same partners in the protein network.

The gene encodes a protein in hair cells, the cells that receive sound inside the ear.

That gene encodes a protein called BAF 180, which is a subunit of the PBAF subtype of the SWI / SNF chromatin remodeling complex.

This gene, along with a number of other genes encoding proteins involved in nickel homeostasis, has been acquired a long time ago by the bacterium via horizontal gene transfer.

Wolfram syndrome is caused by a mutation in the gene encoding a protein called wolframin, which resides in the membrane of the endoplasmic reticulum — another cellular compartment that functions as a manufacturing and packaging system and also acts as a reservoir for calcium ions.

And many genes encode proteins for molecular pumps that spit out foreign molecules — possibly including antibiotics — to detoxify the bacteria.

The mfd gene encodes a protein of 130 kilodaltons and contains the so - called «helicase motifs,» a leucine zipper motif, and regions of sequence similarity to UvrB and RecG proteins.

The BUB1B gene encodes a protein that helps guarantee that the right number of chromosomes are passed from cell to cell.

In the lab strains, the scientists had identified mutations in a gene encoding a protein called cadherin.

This finding is consistent with the recent discovery with several «eukaryotic» signature genes in these archaeal lineages, including genes encoding proteins such as actin, tubulin, and several proteins involved in transcription and membrane deformation.

The gene encodes a protein called apolipoprotein E.

The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin structure, suggesting an aberrant skin barrier as a potential risk factor for atopic dermatitis.

Genes encoding proteins of unknown function constitute 28 % of the essential protein - coding genes set.

He isolated the genes encoding proteins that confer immunological identity to the two main types of cells in the human immune arsenal: the CD4 protein, which dots the surface of helper T cells, and the CD8 protein, which adorns killer T cells.

It has been suggested that a high serum cholesterol level is a risk factor for (AD), and that some polymorphisms of genes encoding proteins regulating cholesterol metabolism are associated with AD development.

Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory.

Excluding genes with homology evidence for immune function, 42.24 % of induced genes encode proteins with bioinformatic evidence for a signal peptide, a significantly higher fraction that the 15.95 % of non-induced and non-immune genes that encode a protein with bioinformatic evidence for a signal peptide (P = 3.4 × 10 − 15, Fisher's Exact Test).

But the real molecular advance came in the late 1980s when, first Scheller while at Stanford University, then Südhof, at the University of Texas Southwestern at Dallas, started to clone and sequence the genes encoding these proteins and to investigate their role in vesicle fusion with the pre-synaptic membrane and neurotransmitter release.

The gene encoding this protein was independently isolated recently and termed B and T lymphocyte attenuator (Btla).

Anna Vorobyeva is characterizing human autism - associated single nucleotide variants (SNVs) in genes encoding proteins that regulate global protein synthesis.

B) Short genes, which includes only genes encoding proteins between 134 and 456 amino acids, inclusive.

We focused on the 26 genes encoding proteins with no blastp hit in D. melanogaster.

All three genes encode proteins that may indirectly interact with human proteins that, in turn, interact functionally with HIV proteins.

This gene encodes a protein, P - glycoprotein that is responsible for pumping many drugs and other toxins out of the brain.

The MDR1 (Multi-Drug Resistant) gene encodes a protein that is responsible for ridding the brain of drugs.

Additional upregulated signal transduction related genes encoded proteins polycystin - 1L1, MLP and LIM regulatory proteins, fibrillins or related proteins containing Ca2 + - binding EGF - like domains, Ca2 + / Mg2 + - permeable cation channel, and other differentially expressed putative transcripts that may play a role in cellular signaling, including known extracellular proteins c - type lectin and collagen (see electronic supplementary material, table S5).

Not exact matches

As the video explains, these traits are due to the tiny molecular machines in our cells known as proteins, which are encoded by bits of DNA called genes.

Humans have roughly 20,000 to 25,000 genes, which encode proteins that perform vital jobs in our cells.

Using a gene - sequencing technique known as whole - exome sequencing that targets only the DNA that encodes proteins, the researchers cataloged virtually every significant DNA variant in three families in which the condition is common.

All animal cells are made up of two genomes, the nuclear genome with 10,000 s of protein coding genes and the mitochondrial genome with 13 protein - encoding genes.

In theory, blocking the production of proteins encoded by these genes could delay or prevent people becoming ill.

This search identified a previously undiscovered gene cluster encoding a new botulinum neurotoxin and accessory proteins in the genome of a species of Enterococcus bacteria isolated from cow faeces.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

The system had come full circle: in flies, whose clocks are the best understood, the CLOCK protein — in combination with a protein encoded by a gene called cycle — binds to and activates the per and tim genes, but only if no PER and TIM proteins are present in the nucleus.

The artist of this depiction, Raquel Lieberman, is the principal investigator of the team that confirmed a Y - shaped structure, the first ever found that was encoded as such by a gene and not constructed out of protein component parts.

Within individual SCN cells, specialized clock genes are switched on and off by the proteins they encode in a feedback loop that has a 24 - hour rhythm.