Because telomere length influences premature aging and cancer, Yildiz's findings bear long - term therapeutic implications.
Because telomeres can vary greatly due to factors such as age, lifestyle and cancer progression, efforts to study the direct associations between cancer risk and telomere length have been difficult.
«Cells do not repair damage to DNA during mitosis
because telomeres could fuse together.»
Because telomeres become shorter as a cell ages, we can test the length of telomeres to gain a picture of the aging process.
(source) This enzyme maintains or lengthen telomeres, which is significant
because telomeres directly impact cellular aging.
Not exact matches
The finding is surprising
because this was not a study of
telomere length.
Because of a quirk in the way the DNA is replicated, the ends are not completely copied, and that information would gradually be lost if not for the
telomeres.
They specifically studied the length of
telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging,
because they shrink over time.
In another clue that cancer cells persist
because they maintain their
telomeres, those cells that started out with longer
telomeres in the experiment lived longer than those with shorter
telomeres.
It is unclear how the entire body is affected
because Spector looked only at
telomeres, nucleotides on the ends of chromosomes that slowly erode as cells copy themselves during normal aging.
According to the new theory, the
telomeres are short in precancerous cells
because telomerase is turned on just enough to maintain but not lengthen the
telomeres.
Deleting
telomere elongation capacity throughout the body would also be life - threatening,
because it would mean that our regular proliferating cells (like those in the skin or the lining of the gut) would suddenly have iron limits on their ability to reproduce themselves and thus replenish tissue.
If cells fail to turn up telomerase, they also fail to immortalize, and eventually die from short
telomeres because chromosomes stick together and then shatter when the cell divides.
This widespread lack of the need for telomerase is used by evolution as a key component of our defense against cancer,
because having a limit to the size and renewal of
telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer.
Yamaki added that it's important for the public to understand that heavy drinking causes
telomere shortening
because «awareness of this fact provides important information necessary for people to live healthier.»
This revealed
telomeres as dangerous structures during mitosis,
because the cells momentarily lost the ability to distinguish between damaged DNA strands and normal
telomeres.
Sometimes telomerase is a good guy
because it helps produce immune cells and stops
telomeres from shortening, but it can also make cells immortal, which prompts them to turn malignant.
Because when Carol [Greider] and I first discovered this enzyme in 1985, we thought of it as being a humble bricklayer that ploddingly puts nucleotides together and builds up this little wall of
telomeres.
Telomeres are important
because they stop chromosomes from «fraying» or clumping together and «scrambling» the genetic codes they contain, performing a role similar to the plastic tips on the end of shoelaces, to which they have been likened.
The myth has a kernel of truth,
because the ends of chromosomes are protected by specialized stretches of DNA called
telomeres.
Telomere shortening occurs in human cells because the enzyme telomerase that adds DNA to the telomere is only active in few cell types, namely stem cells, and is turned off in most other huma
Telomere shortening occurs in human cells
because the enzyme telomerase that adds DNA to the
telomere is only active in few cell types, namely stem cells, and is turned off in most other huma
telomere is only active in few cell types, namely stem cells, and is turned off in most other human cells.
Studies have shown that people following a Mediterranean diet tend to have the healthiest
telomeres,
because of the diet's oxidative and anti-inflammatory effects.
Because Tetrahymena contained so many
telomeres, the organism should provide a rich source of enzymes that act on them, the researchers reasoned.
He added that it's important for people to understand that heavy drinking causes
telomere shortening,
because «awareness of this fact provides important information necessary for people to live healthier.»
This is
because inflammation contributes to the shortening of your
telomeres.
This is of great importance,
because longer
telomeres are strongly associated with longer life.
Because according to her you can't use something like telomerase to increase the length of your
telomeres without significantly increasing your risk of cancer.
As for the average American, no one is going to forego supersizing their hasty meal
because of Neu5Gc, IGF - 1, endothelial progenitor cells,
telomere length, mTOR or TMAO.