Sentences with phrase «because telomere»

Because telomere length influences premature aging and cancer, Yildiz's findings bear long - term therapeutic implications.
Because telomeres can vary greatly due to factors such as age, lifestyle and cancer progression, efforts to study the direct associations between cancer risk and telomere length have been difficult.
«Cells do not repair damage to DNA during mitosis because telomeres could fuse together.»
Because telomeres become shorter as a cell ages, we can test the length of telomeres to gain a picture of the aging process.
(source) This enzyme maintains or lengthen telomeres, which is significant because telomeres directly impact cellular aging.

Not exact matches

The finding is surprising because this was not a study of telomere length.
Because of a quirk in the way the DNA is replicated, the ends are not completely copied, and that information would gradually be lost if not for the telomeres.
They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.
In another clue that cancer cells persist because they maintain their telomeres, those cells that started out with longer telomeres in the experiment lived longer than those with shorter telomeres.
It is unclear how the entire body is affected because Spector looked only at telomeres, nucleotides on the ends of chromosomes that slowly erode as cells copy themselves during normal aging.
According to the new theory, the telomeres are short in precancerous cells because telomerase is turned on just enough to maintain but not lengthen the telomeres.
Deleting telomere elongation capacity throughout the body would also be life - threatening, because it would mean that our regular proliferating cells (like those in the skin or the lining of the gut) would suddenly have iron limits on their ability to reproduce themselves and thus replenish tissue.
If cells fail to turn up telomerase, they also fail to immortalize, and eventually die from short telomeres because chromosomes stick together and then shatter when the cell divides.
This widespread lack of the need for telomerase is used by evolution as a key component of our defense against cancer, because having a limit to the size and renewal of telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer.
Yamaki added that it's important for the public to understand that heavy drinking causes telomere shortening because «awareness of this fact provides important information necessary for people to live healthier.»
This revealed telomeres as dangerous structures during mitosis, because the cells momentarily lost the ability to distinguish between damaged DNA strands and normal telomeres.
Sometimes telomerase is a good guy because it helps produce immune cells and stops telomeres from shortening, but it can also make cells immortal, which prompts them to turn malignant.
Because when Carol [Greider] and I first discovered this enzyme in 1985, we thought of it as being a humble bricklayer that ploddingly puts nucleotides together and builds up this little wall of telomeres.
Telomeres are important because they stop chromosomes from «fraying» or clumping together and «scrambling» the genetic codes they contain, performing a role similar to the plastic tips on the end of shoelaces, to which they have been likened.
The myth has a kernel of truth, because the ends of chromosomes are protected by specialized stretches of DNA called telomeres.
Telomere shortening occurs in human cells because the enzyme telomerase that adds DNA to the telomere is only active in few cell types, namely stem cells, and is turned off in most other humaTelomere shortening occurs in human cells because the enzyme telomerase that adds DNA to the telomere is only active in few cell types, namely stem cells, and is turned off in most other humatelomere is only active in few cell types, namely stem cells, and is turned off in most other human cells.
Studies have shown that people following a Mediterranean diet tend to have the healthiest telomeres, because of the diet's oxidative and anti-inflammatory effects.
Because Tetrahymena contained so many telomeres, the organism should provide a rich source of enzymes that act on them, the researchers reasoned.
He added that it's important for people to understand that heavy drinking causes telomere shortening, because «awareness of this fact provides important information necessary for people to live healthier.»
This is because inflammation contributes to the shortening of your telomeres.
This is of great importance, because longer telomeres are strongly associated with longer life.
Because according to her you can't use something like telomerase to increase the length of your telomeres without significantly increasing your risk of cancer.
As for the average American, no one is going to forego supersizing their hasty meal because of Neu5Gc, IGF - 1, endothelial progenitor cells, telomere length, mTOR or TMAO.
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