Sentences with phrase «because tumour cells»

Because tumour cells are more dependent than their normal neighbours on accelerated nutrient import, these up - regulated transporters could be excellent targets for selective anti-cancer therapies.

These «aggregates» can comprise hundreds of thousands of cells, be up to 2 mm in diameter and be eight times more resistant to chemotherapy drugs — firstly because hypoxic conditions are created inside the aggregates and secondly because these tumour cells reduce growth and are therefore less sensitive.

Not exact matches

Gravekamp thinks the radioactive bacteria affected metastatic tumours most because cells there were still rapidly multiplying, leaving their chromosomes more open to damage than those in healthy tissues or in the original tumour.

Because such cells are derived from adult cells, not pluripotent cells — which have the potential to form a kind of tumour called a teratoma — they might be safer than iPS cells.

That now appears to be because they prompt the growth of the very tumour cells they are meant to kill.

«However, many patients do not respond because myeloid derived suppressor cells (MDSCs), a type of inhibitory cell, are present in the tumour microenvironment.»

That's because the new technique yields cells that have a lower, but not negligible, risk of forming tumours once implanted.

He suggests, instead, that the team take T cells from the site of the tumour, because they would already be specialized for attacking cancer.

«Pancreatic cancer is extremely hard to treat by chemotherapy, so this finding is important because vitamin A targets the non-cancerous tissue and makes the existing chemotherapy more effective, killing the cancer cells and shrinking tumours.

Unlike normal cells, however, the tumour cells are considerably more sensitive, because they can not repair damage well.

Most researchers assumed that this is because a few rogue cancer cells find ways to circumvent the drugs before the whole tumour has been killed off.

Lead author Moustafa Abdalla writes: «Almost all genomic studies of breast cancer have focused on well - established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells.»

Patients with TILs do much better because they already have cancer - fighting cells in their tumours.

Treatment is difficult because pancreatic tumours are protected by an armour of connective tissue, blood vessels and immune cells, known collectively as the stroma.

«This is because the stress led to poor function against the cancer by T - cells, which are very important in the immune system's control and surveillance of tumours and are a major target in many immunotherapy treatments.»

Other safety strategies include improving the specificity of CAR T - cells for tumour cells because healthy cells also carry CD - 19 receptors.

Willet, Mills, and their colleagues believe the discovery that cells in different organs go through the same process to become proliferative could lead to new potential targets for cancer treatment because the factors that initiate tumours could be the same in multiple organs.

Tumour cells are «glutamine - addicted» [1,2] because glutamine is coupled to mechanistic target of rapamycin (mTOR) signalling, which integrates signals from growth factors, energy status and amino acid nutrition and co-ordinates these signals with cell growth, cell cycle progression and antioxidant machinery [3].

Targeting CTCs, the cells responsible for spreading cancer, is important because they carry information from the primary tumour that can inform treatment; however, they are outnumbered by a billion - to - one by normal cells in a patient» blood and are therefore extremely challenging to capture.

Because FeLV hijacks the cells» replicating machinery, it is not surprising that this disease can ultimately lead to tumour growth.