Sentences with phrase «binding of adenosine»

The adenosine A ₂ ₐ receptor is the main adenosine receptor expressed on immune cell subsets including T - cells, NK cells and dendritic cells and binding of adenosine to the A ₂ ₐ receptor on immune cells blocks the activation and effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.

Binding of adenosine to the A2A receptor on immune cells blocks the activation and effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.

Not exact matches

Bound to the cell membrane, Na ± K+ATP ase uses the energy of adenosine triphosphate (ATP) molecules to pump sodium out of the cell and potassium into the cell, maintaining a charge gradient that allows ions to flow through open channels.

In this pathway, dopamine - and an adenosine 3 ′, 5 ′ - monophosphate (cAMP)-- regulated phospho - protein of 32 kilodaltons (DARPP - 32) is phosphorylated or dephosphorylated at three sites, in a pattern predicted to cause a synergistic inhibition of protein phosphatase — 1 and concomitant regulation of its downstream effector proteins glycogen synthesis kinase — 3 (GSK - 3), cAMP response element — binding protein (CREB), and c - Fos.

In a new report published in the January 2015 issue of the FASEB Journal, scientists use mice to show that a human membrane - bound enzyme called CD39, which can clear the dangerous buildup of adenosine triphosphate (ATP) from the bloodstream, significantly improves survival of mice in sepsis.

MinE activates the enzymatic activity of membrane - bound MinD, thus triggering the conversion of its bound nucleotide adenosine triphosphate (ATP) to adenosine diphosphate (ADP), which causes the release of MinD - ADP into the cell cytoplasm.

When a substance is bound to zebrafish Abcb4, this triggers cleavage of the energy transfer substance adenosine triphosphate (ATP).

The Escherichia coli methyl - directed reaction has been reconstituted in a purified system consisting of MutH, MutL, and MutS proteins, DNA helicase II, single - strand DNA binding protein, DNA polymerase III holoenzyme, exonuclease I, DNA ligase, along with ATP (adenosine triphosphate), and the four deoxynucleoside triphosphates.

Two specific long - range interactions clamp the two halves of the domain together: a two - Mg2 + - coordinated adenosine - rich corkscrew plugs into the minor groove of a helix, and a GAAA hairpin loop binds to a conserved 11 - nucleotide internal loop.

The Mfd protein was shown to (i) displace RNAP stalled at a lesion in an adenosine triphosphate - dependent reaction, (ii) bind to the damage recognition subunit (UvrA) of the excision nuclease, and (iii) stimulate the repair of the transcribed strand only when transcription is taking place.

[1,5,7] The direct inhibition of cdks 1, 2, and 4 via competitive inhibition of adenosine triphosphate binding by flavopiridol has been demonstrated.

«They always include an adenosine triphosphate binding site and a set of conserved amino acid residues.

It binds to the receptors, substituting adenosine, which in turn prevents the increase of pain levels.

This happens because of caffeine's affinity to bind with adenosine receptors in the muscles.

Now adenosine is a neurotransmitter and it's an inhibitory neurotransmitter and what that means is that it suppresses the level of the activity of the neurons that it interacts with so if we take the caffeine molecule and we block the ability of the adenosine molecule to bind to the receptor, to the adenosine receptor, we keep ourselves more alert, we keep adenosine from binding.

It is found in all human cells where it is required to bind to and activate adenosine triphosphate (ATP), the chief energy molecule of cells.

For a chemical perspective adenosine triphosphate is an adenine nucleotide, which binds itself to 3 different groups of phosphatee types.