The PI
of the proposal has also experience in cheminformatics method
development for chemical
biology and therapeutic
development (Mueller, R., et al.; «Discovery
of 2 -(2 - Benzoxazoyl amino)-4-Aryl-5-Cyanopyrimidine as Negative Allosteric Modulators (NAMs)
of Metabotropic Glutamate Receptor 5 (mGlu5): From an Artificial
Neural Network Virtual Screen to an In Vivo Tool Compound»; ChemMedChem; 2012; 7; 406).