«
Brain development disorders in children linked to common environmental toxin exposures.»
Not exact matches
But it's becoming increasingly clear that the effects are serious, and range from momentary unconsciousness, confusion and memory loss — such as that suffered by Kramer — through to whiplash, debilitating headaches, and
in the longer term the
development of any number of emotional distresses and
disorders linked to
brain trauma.
«This process may therefore play a key role
in neural
development and central nervous system function
in adults, as well as
in chronic
brain disorders and various acute
brain injuries.»
2) Last Child
in the Woods: Saving Our Children From Nature - Deficit
Disorder by Richard Louv — read this concurrently with # 3 3) Smart Moves: Why Learning Is Not All
in Your Head by Carla Hannaford — which will probably lead to curiosity about # 4 4)
Brain Gym or similar therapies offered by # 5 and # 6 5) The National Association for Child
Development -LRB--RRB- 6) The Developmental Movement Center, Seattle (206) 525-8038 ″
Dr. Perry's research includes: the effects of prenatal drug exposure on
brain development, the neurobiology of human neuropsychiatric
disorders, the neurophysiology of traumatic life events, and long - term cognitive, behavioral, emotional, social and physiological effects of neglect and trauma
in children, adolescents and adults.
Dr. Giedd's research team seeks to use cutting edge technologies to explore the relationship between genes,
brain and behavior
in healthy
development and
in neuropsychiatric
disorders of childhood onset.
Professor Jianfeng Feng commented that new technology has made it possible to conduct this trail - blazing study: «human intelligence is a widely and hotly debated topic and only recently have advanced
brain imaging techniques, such as those used
in our current study, given us the opportunity to gain sufficient insights to resolve this and inform
developments in artificial intelligence, as well as help establish the basis for understanding and diagnosis of debilitating human mental
disorders such as schizophrenia and depression.»
If the molecules are pulled into an immune function
in the fetus, she says, it could disrupt
brain development and lead to neurodevelopmental
disorders.
If clinicians could use
brain scans to identify vulnerable high - risk individuals
in early adolescence when the
brain is still developing, it may be possible to curb the
development of the
disorder and help prevent its most debilitating effects.
For example, knowing the precise
brain activity involved could shed light on
disorders in which body awareness is disrupted, such as schizophrenia, and help with the
development of prosthetic limbs that are more easily incorporated into body image.
If the zinc ions or the transcription factor MTF1 were specifically inhibited
in the
brain, it is possible that the
development of a seizure
disorder could be prevented.
«The project's goal is to accelerate the
development of technologies for mapping the
brain's circuitry
in animal models, specifically
in the marmoset monkey, whose neural circuits are much closer to human compared with rodent models, and to connect the results to the diagnosis and treatment of human neurological
disorders and mental illness.»
They have also used state - of - the - art information about
brain development to accurately pinpoint new genes and biological pathways implicated
in this
disorder.
For example,
brain anatomy could be more closely monitored
in those people where there is suspicion of an increased risk of developing a mental
disorder (the children of parents with mental health problems, for example), so that the probability of developing a pathology that interferes with their normal
development can be estimated.
Scientists working
in the Smurfit Institute of Genetics at Trinity College Dublin and the Department of Psychiatry, RCSI, have discovered that abnormalities
in the integrity of the BBB may be a critical component
in the
development of schizophrenia and other
brain disorders.
Like misdirected letters and packages at the post office, the neurons made from bipolar
disorder patients also differed
in how they were «addressed» during
development for delivery to certain areas of the
brain.
German and Canadian scientists have built a three dimensional map of the human
brain to help
in the
development of new treatments for neurological
disorders like Alzheimer's and Parkinson's disease.
So, the new findings support the idea that genetic differences expressed early during
brain development may have a lot to do with the
development of bipolar
disorder symptoms — and other mental health conditions that arise later
in life, especially
in the teen and young adult years.
It is a big idea that could help unravel mysteries of
brain development and evolution, and help link neurological and psychiatric
disorders to abnormalities
in brain structure.
«The idea that psychiatric
disorders were caused by problems
in brain development was a little bit radical.
The critical role these changes play
in brain development highlights the importance and urgency
in understanding neural circuits
in more detail and suggests new avenues for investigating the underlying causes of developmental
disorders such as autism.
The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease
in which disruptions of certain genes during
brain development contribute to a person's risk for multiple psychiatric
disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.
Abnormalities
in brain structure during critical periods
in development have often been associated with negative outcomes, such as learning disabilities and behavioral
disorders.
Preclinical studies suggest that Cdk5 is a gene that is important for the normal wiring of the
brain during early
development and may be involved
in some neurodegenerative
disorders, including ALS, Parkinson's and Alzheimer's disease.
If these mutations happen during embryonic
development, there could be several neurological problems: the child could become autistic, kids could be born with seizure
disorder, or the developing neurons might not migrate to their proper site
in the
brain.
Neurocutaneous
disorders are caused by abnormal
development of cells
in the embryonic stage, leading to tumors
in various parts of the body, including the skin, organs, bones,
brain and spinal cord.
Many of the eight genes are active during
brain development and may play a role
in neuropsychiatric
disorders such as autism and schizophrenia, Sanders says.
Exposures of pregnant women and children to common thyroid - hormone - disrupting toxins may be linked to the increased incidence of
brain development disorders, according to a review published
in Endocrine Connections.
Recent research discoveries
in the
development of
brain disorders could pave the way to new therapies for treating seizures, and even some children with autism, says a leading oncologist and researcher at the University of Alberta.
«Some neuropsychiatric
disorders, such as schizophrenia and autism, are characterized by the abnormal
development of synaptic connectivity
in certain key parts of the
brain,» explains Schneggenburger.
«This study offers new insights about the
brain in AN, which we are using to guide treatment
development efforts, and reduce stigma associated with this life - threatening
disorder,» added Kaye, who is a Professor of Psychiatry and Director of the Eating Disorder Program
disorder,» added Kaye, who is a Professor of Psychiatry and Director of the Eating
Disorder Program
Disorder Program at UCSD.
But researchers are beginning to uncover a biological explanation for the problem: they have found a gene that may contribute to its
development as well as a pathological signature of the
disorder in the
brain.
Though these findings have been obtained
in mice, the scientists hypothesize that disrupted coordination between the
development of the microglia and that of the
brain contributes to an increased risk of such neurodevelopmental
disorders as autism and schizophrenia
in human beings.
The involvement of this enzyme
in susceptibility to oxidative stress, which has frequently been observed
in autistic children, its association with gastrointestinal diseases — which often accompany autistic
disorders — and its role
in nerve
development and neurotransmission mean it is an ideal candidate for deregulation of its expression to lead to the abnormal
brain development observed
in ASD.
Scientists studying
brain diseases may need to look beyond nerve cells and start paying attention to the star - shaped cells known as «astrocytes,» because they play specialized roles
in the
development and maintenance of nerve circuits and may contribute to a wide range of
disorders, according to a new study by UC San Francisco researchers.
A new study led by scientists at The Scripps Research Institute (TSRI) is giving researchers a first look at the early stages of
brain development in patients with Fragile X syndrome, a
disorder that causes mild to severe intellectual disability and is the most common genetic cause of autism spectrum
disorder.
In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorder
In the new study, the researchers discovered that during the second trimester of human
brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects
in which have previously been implicated in autism and several other psychiatric disorder
in which have previously been implicated
in autism and several other psychiatric disorder
in autism and several other psychiatric
disorders.
«The method thus opens up completely new opportunities for investigating
disorders in the architecture of the developing human
brain,» explains Dr. Julia Ladewig, who leads a working group on
brain development.
The cause of his
disorder has yet to be pinpointed, but it almost certainly stems from a problem
in the early
development of his
brain.
Similarly, Neanderthal variants impacting
development of a particular suspect
brain area may help to inform cognitive disability seen
in certain
brain disorders, say the researchers.
They're now reporting
in ACS» Journal of Agricultural and Food Chemistry that a compound from hops could protect
brain cells from damage — and potentially slow the
development of
disorders such as Alzheimer's and Parkinson's diseases.
«Inflammation has been shown to alter
brain development in previous studies, and schizophrenia is a neurodevelopmental
disorder.
Reductions
in cortical folding may reflect alterations
in brain development early
in life
in these
disorders.
Increased expression of a gene linked to autism spectrum
disorders (ASDs) leads to a remodeling of dendrites during
brain development, according to a new study conducted
in cultured neurons and an ASD mouse model published
in JNeurosci.
White matter fibers connect the different areas of the
brain and abnormalities
in white matter may be tied to the
development of dementia and other cognitive
disorders.
The Program for Neuropsychiatric Research (PNPR) at McLean Hospital, founded
in 2004 by Dr. Bruce Cohen, is a consortium of investigators and clinicians using laboratory,
brain imaging, and clinical techniques to increase understanding of the causes of psychotic, mood, and related psychiatric
disorders and use that knowledge to guide the
development of improved treatments.
Gladstone investigators also discovered that the p75 neurotrophin receptor — a protein long known for its role
in the
development of
brain cells — plays unexpected roles
in metabolic
disorders, such as type 2 diabetes.
Belmont, MA -
In an unprecedented move, McLean Hospital, the largest psychiatric affiliate of Harvard Medical School, and Israel's Weizmann Institute of Science, a world leader in brain research, are launching an alliance that will lead to further understanding of neuropsychiatric disorders and accelerate the development of corresponding treatment
In an unprecedented move, McLean Hospital, the largest psychiatric affiliate of Harvard Medical School, and Israel's Weizmann Institute of Science, a world leader
in brain research, are launching an alliance that will lead to further understanding of neuropsychiatric disorders and accelerate the development of corresponding treatment
in brain research, are launching an alliance that will lead to further understanding of neuropsychiatric
disorders and accelerate the
development of corresponding treatments.
Researchers studying worms have discovered new information on a gene that is involved
in the
development of Joubert syndrome, a genetic
disorder that affects the
brain stem.
Lindsley, who also is professor of Pharmacology, Biochemistry and Chemistry
in the medical school and College of Arts and Science, has helped pioneer
development of drug - like compounds that, by adjusting the activity of receptors
in the
brain, may lead to new treatments for a wide range of
brain disorders.