Brain metabolism different than the metabolism of other organs and it appears that ketone metabolism in the brain conveys a therapeutic benefit in many neurological conditions.
Not exact matches
Secreted by certain
brain cells, APOE is known to regulate cholesterol
metabolism within the
brain and can bind to A-beta peptides, suggesting that the
different forms of the protein may affect whether and how toxic A-beta plaques form.
«Using novel computational methods, we have pointed to new biological pathways that act in the
brain to regulate overall obesity, and also to a
different set of pathways related to fat distribution that regulate key metabolic processes,» says senior author Joel Hirschhorn, M.D., Ph.D., Concordia professor of pediatrics and professor of genetics at Boston Children's Hospital and Harvard Medical School, and co-director of the Broad Institute
Metabolism Program.
Drugs that reduce cholesterol levels in the cardiovascular system can strongly benefit people with diabetes or related conditions, but cholesterol in the blood generally can't cross into the
brain, and cholesterol
metabolism is quite
different in the
brain, she points out.
EFAs or essential fatty acids play a very important role in
different body functions like cell maintenance,
brain development, transportation of oxygen from the lungs to the bloodstream, regulation of
metabolism and mood, regulation of insulin sensitivity, as well as hormone production.