Brain metastases often manifest years after the primary tumour.
Not exact matches
While therapies that target HER2 and HER3 are clinically available, clinical trials
often exclude patients with
brain metastases.
«Metastatic
brain tumors —
often from lung, breast or skin cancers — are the most commonly observed tumors within the
brain and account for about 40 percent of advanced melanoma
metastases.
«Metastatic
brain tumors —
often from lung, breast or skin cancers — are the most commonly observed tumors within the
brain and account for about 30 percent of advanced breast cancer
metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and Imaging Laboratory in the MGH Departments of Radiology and Neurology, who led the study.
Furthermore, while it is true that metastatic melanoma is a systemic disease — and also that mortality is not caused by dermal or subcutaneous lesions but rather by
metastases to the liver,
brain, lung, and other sites — locoregional disease is
often disfiguring and painful, and locoregional therapy may provide clinical benefit.