Brain structure abnormalities in young women who presented conduct disorder in childhood / adolescence.
Brain structure abnormalities in adolescent girls with conduct disorder.
Additionally,
the brain structure abnormalities identified in this study reflect those found in children with depression or at high risk for developing the disorder, suggesting that these alterations may be why children of mothers with perinatal depression are more vulnerable to depression later in life.
Not exact matches
Since the first human
brain organoids were created from stem cells in 2013, scientists have gotten them to form
structures like those in the
brains of fetuses, to sprout dozens of different kinds of
brain cells, and to develop
abnormalities like those causing neurological diseases such as Timothy syndrome.
Among the 42 Zika - infected women in the study, 12 were carrying fetuses with severe
abnormalities, including absence or withering of
brain structures, tissue death, restricted growth and, in one case, microcephaly.
Severe CTE was defined as tau clusters and several other degenerative
abnormalities affecting not only the cortex, but deeper
brain structures including the hippocampus, the amygdala, and the
brain stem.
It is a big idea that could help unravel mysteries of
brain development and evolution, and help link neurological and psychiatric disorders to
abnormalities in
brain structure.
Abnormalities in
brain structure during critical periods in development have often been associated with negative outcomes, such as learning disabilities and behavioral disorders.
«We wanted to find the link between the abnormal
structure of synapses in the FXS mouse, and the behavioral
abnormalities at the level of
brain circuits; that had not been previously established,» said senior author Dr. Carlos Portera - Cailliau, an associate professor in the departments of neurology and neurobiology.
In recent decades a rapid expansion in knowledge has occurred about the
brain circuits that process and regulate emotional behavior, and in which
abnormalities of neural function and
structure associate with mood disorders.
Dr. Rapoport was a pioneer in studying the pathophysiology of ADHD and neuropharmacological approaches to its treatment, and she was the first to discover that some childhood psychiatric symptoms result from autoimmune reactions to streptococcal infection, the first to establish the link between obsessive - compulsive behaviors in children and OCD in adults, and the first to use longitudinal magnetic resonance imaging to uncover developmental
abnormalities in
brain size and
structure in children with schizophrenia.