Sentences with phrase «c allele»

BtsI cleaves the amplicon only in individuals having the c. 1010T > C allele, yielding fragments of 204 bp and 266 bp.

Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele.

«Lower BDNF levels may contribute to obesity in people with the C allele.

In African American adults, the team found that the C allele was associated with higher BMI and body fat percentage in those with CT or CC types.

Overall, the study suggests that the C allele of the BDNF gene may be linked to obesity in people.

To understand why the C allele has an effect on obesity, the study team carefully examined the genetic area that differs between C and T alleles.

Finally, in a group of Hispanic children, the researchers found that the C allele (CT, CC types) was associated with a higher BMI score.

There was a dominant effect of the C allele in response to breastfeeding.

(2) The prevalence of the MTHFR A1298C associated 3 genotypes and A / C alleles in the recurrent miscarriage group did not differ significantly from the control.

Not exact matches

The recessive s (susceptible) allele is found in AKR / J, C57BL / 6, BALB / c, CBA / J, NFS, NZB and 129 / J.

The allele Rmcfr determines resistance and occurs in strains DBA / 1, DBA / 2, and CBA / Ca; the allele Rmcfs determines susceptibility and occurs in strains AKR / J, C57BL / 6, BALB / c, CBA / J, NFS, NZB, 129 / J, and many others.

Here, using an inducible Cre, nuclear LacZ reporter allele knocked into the Prom1 locus (Prom1 (C - L)-RRB-, we show that Prom1 is expressed in a variety of developing and adult tissues.

Lineage - tracing studies of adult Prom1 (+ / C - L) mice containing the Rosa26 - YFP reporter allele showed that Prom1 (+) cells are located at the base of crypts in the small intestine, co-express Lgr5 (ref.

Activation of endogenous Wnt signalling in Prom1 (+ / C - L) mice containing a Cre - dependent mutant allele of beta - catenin (Ctnnb1 (lox (ex3)-RRB--RRB- resulted in a gross disruption of crypt architecture and a disproportionate expansion of Prom1 (+) cells at the crypt base.

Each allele eliminated the pathogenic p.K1872X mutation and removed 59 or 22 amino acids from the predicted encoded protein, while restoring the open reading frame to encode the critical C terminal region of BRCA2 (Fig. 1C, labeled D1 and D2, Supplementary Tables S1 and S2).

Yet each one tells a different story: (a), how novel - to - dbSNP variants were rare; (b), how nonsynonymous variant frequencies are shifted to lower values relative to those of synonymous variants, (c), how this shift in allele frequencies is more pronounced for damaging nsSNPs, consistent with natural selection, and (d), how the sizes of observed indels are enriched for non-frameshift events divisible by 3.

31) Soh J, Okumura N, Lockwood WW, Yamamoto H, Shigematsu H, Zhang W, Chari R, Shames D, Tang X, MacAulay C, Varella - Garcia M, Vooder T, Wistuba II, Lam S, Brekken R, Toyooka S, Minna JD, Lam WL, Gazdar AF (2009) Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

Alleles associated with lower levels of low density lipoprotein cholesterol (LDL - C) have recently been associated with an increased risk of type 2 diabetes (T2D), highlighting the complex relationship between LDL - C and diabetes.

This observation begs the question whether LDL - C - raising alleles are associated with a decreased risk of T2D.

Dogs need at least one copy of the «T» allele to have a wavy or curly coat; the ancestral «C» allele is associated with a straight coat.

The affected dogs (A) are homozygous for the dodecamer repeat expansion mutation with multiple dodecamer repeats, carrier (C) dogs have the normal and mutated allele and clear dogs (WT) have three copies of the repeat [8]

The cream dilution gene is has two alleles: C which does not have any effect on either red or black pigment, and Ccr which dilutes red pigment significantly and black pigment slightly.

The dog could be a carrier with a false allele (but because of how markers are inherited it will never be a Pattern B; it's still a Pattern C).

Pattern B and C uncertainties are due to the test detecting a false allele.

The C locus affects the depth of yellow - red coat pigment, not its presence or absence (though two ch «chinchilla» alleles might produce near - white dogs in some breeds).

The DRD2 polymorphisms were scored by two independent observers, where the T - probe signal corresponded to the TaqIA - 1 allele and the C - probe signal corresponded to the TaqIA - 2 allele.

Participants homozygous for the major allele (CC) were more likely to have high CU traits than heterozygotes (C / T) or minor homozygotes (TT).

Participants homozygous for the major allele (CC) of SNP rs6314 were more likely to have high CU traits than heterozygotes (C / T) or minor homozygotes (TT).