Sentences with phrase «cb2 agonist»

In rats that developed neuropathic pain from chemotherapy, a CB2 agonist (a molecule that binds strongly to the CB2 receptor and activates it) continued to relieve pain despite repeated dosing.

She envisions that chronic pain patients may benefit from the combined pain relief of a CB2 agonist and a low - dose opioid.

Now Hohmann is trying to determine what cell activity is responsible for the therapeutic properties of CB2 agonists.

Not exact matches

Following postdoctoral training at the State University of New York, Stony Brook with Masayori Inouye, he joined the Schering - Plough Department of Immunology, where he characterized the biology of a new class of cannabinoid CB2 receptor - specific inverse agonists.

CB2 cannabinoid agonists such as WIN55,212 - 2 inhibit experimental autoimmune encephalomyelitis (EAE), an animal model of MS, by mediating apoptosis of the encephalitogenic cells that induce brain inflammation (41).