Sentences with phrase «cd4 cell counts»

In this analysis alone, intake CD4 cell counts (t = − 2.1, P <.04) and Karnofsky severity (t = − 2.2, P <.04) were associated with endpoint BDI score, and the post hoc Tukey least significant difference test showed a trend for CBT to outperform SP (P =.06).

There was no association between symptoms of depression and severity of HIV infection measured by CD4 cell counts, HIV viral load and the duration of time since the diagnosis of HIV infection.

People with CD4 cell counts below 350 per millilitre of blood can now be treated.

All of these groups will receive treatment whatever their CD4 cell counts.

One of the studies, published in 2008, suggested that patients whose antiretroviral treatment was deferred until their CD4 cell counts were below 250 were at greater risk of opportunistic infection than those that received antiretroviral treatment when CD4 cell counts were higher than 350.

The patients were in category C - 3 with CD4 cell counts below 200 and each had at least one case of AIDS - defining illness.

Instead of a CD4 cell count of 200, the threshold which the WHO recommended in its 2006 guidelines for HIV treatment, a CD4 cell count at or below 350 should be the cutoff, the agency now advises.

To investigate that response in the context of HIV, the study grouped women by their CD4 cell count, a measure of immune system health.

Such low concentrations of plasma zinc have been linked with disease progression, independent of baseline CD4 cell count, lymphocyte concentrations and age - and calorie - adjusted dietary intake (Falutz et al. 1988, Graham et al. 1991).

Mortality, CD4 cell count decline, and depressive symptoms among HIV - seropositive women: longitudinal analysis from the HIV epidemiology research study

Initial Karnofsky score correlated with the final Ham - D (r = −.27, P =.009, n = 94) and BDI (r = −.25, P =.02, n = 95) scores, suggesting patients with greater physical dysfunction responded best; CD4 cell count was not significantly correlated.

To ascertain whether medical status influenced antidepressant outcome, we repeated analyses using as covariates intake Karnofsky score and CD4 cell count in addition to initial Ham - D or BDI score.

Baseline mean Karnofsky score was 80 ± 6.5; CD4 cell count, 280 ± 222 (n = 99).

Outcome assessments were the 24 - item Ham - D and Beck Depression Inventory (BDI14), to measure depressive symptomatology; CD4 cell count; and the clinician - administered, 100 - point Karnofsky scale15 to assess physical functioning.

Mean scores on the 24 item HAM - D, Beck Depression Inventory (BDI), and 100 point Karnofsky scale; and CD4 cell count.

The groups did not differ when adjustment was made for CD4 cell count and Karnofsky physical functioning score.

Not exact matches

The new recommendations will likely result in more patients worldwide obtaining treatment, based on their CD4 immune cells counts.

He treated nine men who had been hiv positive for 20 years or more, were on combination antiretroviral therapy, and yet had persistently low counts of the cd4 cells, signaling the continued presence of the virus.

Those infected with poorly replicating viruses progressed to low CD4 T cell counts more than two years after those infected with highly replicating viruses.

In the other, infected partners deferred treatment until their CD4 T cells (the immune cells the virus targets) fell to a perilous count below 250, or until they suffered an AIDS - related illness.

The human intestine has the highest concentration of HIV target cells, the majority of which are destroyed within days of infection, and before CD4 T cell counts drop measurably in the blood.

The groups also were matched on maternal viral load and CD4 T cell counts (which are clinical factors known to effect transmission).

All 45 animals successfully engrafted; however, one animal that received cells treated with the X4 - ZFNs had a significantly higher but stable CD4 + T cell count and was thus excluded as an outlier from the remainder of the study.

(A) CD4 + T cell counts were measured every 7 — 10 days post infection.

Human CD4 + T cell counts were determined by staining 50 µl of whole blood in Trucount tubes (BD) with anti-CD45 FITC (Biolegend), anti-CD3 Qdot 655 (Invitrogen), anti-CD4 Alexa Fluor 700, anti-CD8 Pacific Blue (Biolegend), and anti-CXCR4 PE - Cy5.

To determine if X4 - ZFNs impacted cell growth or viability in the absence of HIV, we first compared CD4 counts over time between the uninfected X4 - ZFN and R5 - ZFN control mice.

Engraftment was assessed by peripheral blood CD4 + T cell counts 27 days post-injection.

The CDC rules that a cell count of less than 200 CD4 (T4) cells / mm3 combined with an HIV - positive status defines AIDS.

Such individuals, then called HIV long - term non-progressors, were defined by their lack of HIV - related symptoms and high CD4 T cell counts that remained stable for periods of 7 years or longer.

Use of CXCR4 as a co-receptor is associated with a marked drop in CD4 + T - cell counts [19].

Patient had cryptococcal meningitis and a CD4 count of 24 cells / µl at the time of virus isolation.

CD4ζ - hESC - NKs cells were observed in peripheral blood early at day 6 at which point CD4 T - cell counts rose compared in NK treated mice compared to control, which gained significance by day 12, demonstrating suppression of HIV activity.

AIDS is diagnosed when the CD4 count falls below 200 cells per cubic millimeter of blood.