Parents, full siblings, and offspring of
a CEA carrier should be tested When it is determined which parent of a DNA tested carrier is the source of the mutation the half - siblings through that parent should also be tested.
No male that is
a CEA carrier should be used extensively at stud.
Not exact matches
Tested to determine the progressive rod - cone (prcd) / PRA and
CEA (collie eye anomaly) DNA status «Clear,
Carrier or Affected» if unknown by parentage.
The parents, full siblings, and offspring of
CEA affected dogs or identified
carriers should be tested if they are to be used for breeding.
Two thirds of the normal littermates will be
carriers, so it is very important to know whether or not
CEA is present in any given litter.
When there is a DNA test, all a breeder has to do to make sure he never produces a puppy with a recessive disease like
CEA is breed
carriers only to mates that have been DNA tested clear.
All affected animals have two genes for
CEA; therefore both of their parents are
carriers.
Subsequently, all puppies from identified
carriers should be DNA tested for
CEA if they will be used for breeding.
Dogs with two copies of the mutation have
CEA, those with one are normal
carriers and those with none are clear.
In the 1980s a few well - used sires happened to be
carriers and for a while
CEA was topic - one among our inherited health issues.
All that is required to make
CEA a major breed health issue again is a single popular sire who happens to be a
carrier.
If the disease is uncommon, as with the progressive rod - cone degeneration (PRCD) form of Progressive Retinal Atrophy in Australian Shepherds, or if use of a test and careful breeding decisions have markedly reduced the frequency of a formerly common mutation (think what could be done with
CEA in Collies,) testing could then be confined to only those dogs with known family history of the disease or with relatives that have been DNA tested as
carriers.
If a dog is determined to be a
carrier of
CEA, either through testing or because it has affected offspring, it should be bred but only to a mates that have been tested clear of the mutation.
The
CEA - CH DNA test determines if your dog is normal, a
carrier, or actually affected by Collie eye defect.