A dog with two copies of the normal CEA /
CH gene is homozygous normal.)
Not exact matches
In fact,
CH methylation within a
gene correlated more highly with repression than inaccessibility of DNA to transcription machinery (as measured by the ability of a transposase to grab onto
genes).
Since all dogs with CEA have
CH it can be managed in the same way one would manage any single
gene recessive trait even though other as - yet unidentified
genes cause the more serious defects.
Reduction or even elimination of the CEA /
CH mutant
gene can be viewed as a longer - term goal.
This breeding should theoretically concentrate «
Ch Blue Boy's»
genes slightly more than other dogs in the pedigree.
Even though this
gene does not by itself cause the more serious defects, dogs that do not have two copies of the
CH mutation will not develop CEA defects.
The other (still unidentified)
genes only contribute to the trait if two copies of the CEA -
CH mutation are present.
CH is caused by a recessive
gene mutation.