Sentences with phrase «cns disorders»

It is used in the management and treatment of immune mediated disease such as immune mediated hemolytic anemia, or thombocytopenia: many CNS disorders: some neoplasia: dermatologic diseases: allergic reactions such as asthma, hives, and itching: inflammatory orthopedic diseases: endocrine disorders including Addison's: respiratory disease with an inflammatory component, inflammatory bowel diseases and many other conditions.

«Animal studies suggest that a diet rich in phytochemicals may enhance neuroplasticity and resistance to neuroinflammation, mitigating or preventing neurodegenerative changes in the brain that are typical in a number of age - related CNS disorders (including PD).

The collaboration will combine Lysogene's outstanding translational and clinical expertise in gene therapy for CNS disorders with the unique preclinical expertise and infrastructure of UMMS and AU to design and test innovative AAV - based gene therapy approaches to treat GM1 - gangliosidosis.

Dr. Leiser has over 10 years of experience in drug discovery and applying translatable neurophysiological biomarkers in diverse drug discovery projects across CNS disorders including schizophrenia, Alzheimer's, depression, epilepsy.

Our results suggest that a pandemic H5N1 pathogen, or other neurotropic influenza virus, could initiate CNS disorders of protein aggregation including Parkinson's and Alzheimer's diseases.

That noteworthy advance could have huge implications for those with brain and other CNS disorders one day.

Not exact matches

The disease is characterized by the accumulation of very long chain fatty acids (VLCFA) leading to a neurodegenerative disorder that is chronically debilitating and life - threatening, where the most affected tissues are the myelin in the central nervous system (CNS) and the adrenal cortex.

The clinical - stage biopharmaceutical company committed to developing novel medicines to transform the lives of patients with life - altering central nervous system (CNS) disorders, SAGE Therapeutics Inc. (NASDAQ: SAGE) seem to be poised for a price surge as per its latest charts.

Decades of research on this autoimmune disorder opened a window into how the immune system and the CNS interact, but more recent research efforts have revealed the exceptionally broad scope of communication between the two.

The immune system's reach within the CNS is extensive, probably contributing to the initiation and pathogenesis of neurodegenerative diseases, neurodevelopmental disorders such as autism, and mental health disorders such as schizophrenia.

These drugs are also frequently used to manage central nervous system (CNS) disorders associated with a pathologically permeable BBB, such as with brain tumors and multiple sclerosis.

PsychoGenics is a Preclinical CRO with expertise in the CNS and orphan disorders.

For the first time, researchers have discovered that non-gene mutations could cause rare developmental disorders of the CNS.

Cell biology chair Gary Bassell was interested in the disease, because it's a triplet repeat disorder, similar to fragile X syndrome, yet the CNS mechanisms and symptoms are very different.

Indeed selected compounds demonstrated efficacy in several animal models of CNS related disorders such as depression, obesity, addiction, and psychosis.

Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criteria

De Smaele E, Ferretti E, Gulino A. MicroRNAs as biomarkers for CNS cancer and other disorders.

Selective 5 - hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs in several animal models of CNS related disorders.

Overall, 89 of 363 episodes were categorized as CNS infection (25 %; most commonly viral meningitis [7 %], bacterial meningitis [7 %], and viral encephalitis [4 %]-RRB-, 36 (10 %) episodes as CNS inflammatory disorder, 111 (31 %) as systemic infection, in 119 (33 %) as other neurological disorder, and 8 (2 %) as other systemic disorders.

The reference standard was the diagnosis classified into five categories: 1) CNS infection; 2) CNS inflammation without infection; 3) other neurological disorder; 4) non-neurological infection; and 5) other systemic disorder.

I am a Certified Nutritionist (MS, CN) and mental health therapist with a specialty in disordered eating.

Ketogenic diets have a long history of efficacy for disorders of the CNS, most notably epilepsy.46, 47 KBs are more efficient than glucose and induce less oxidative damage.47 Additionally, KBs are brought into the brain by monocarboxylate transporters — independently of glucose and insulin — so their uptake is not hindered when insulin signaling fails.51

Christine interviews certified nutritionist Amy Berger, MS, CNS, NTP, about the latest research on ketogenic diets and their applications to neurological disorders including dementia, ALS and MS as well as cancer and...

There is emerging evidence for acne, PCOS, exercise performance, wound healing, longevity, cancer, CNS Oxygen Toxicity, autism, Angelman's Syndrome, ALS, MS, Neuropathies, Alzheimer's disease, brain injury, neurodegeneration, anxiety, depression, bipolar and schizoaffective disorder.

Through his observations of patients with neurological disorders and chronic musculoskeletal pain, Janda found that the typical muscle response to joint dysfunction is similar to the muscle patterns found in upper motor neuron lesions, concluding that muscle imbalances are controlled by the CNS (Janda 1987).

Dr. Mark Flannery, DC, FAAIM, DCBCN, DCCN, CNS has helped many patients suffering with Hashimoto's hypothyroidism, multiple sclerosis, rheumatoid arthritis, vitiligo, chronic fatigue, fibromyalgia, digestive disorders and other autoimmune, chronic, and neuro - inflammatory conditions, improve their quality of life.

This new understanding of the ENS - CNS connection helps explain the effectiveness of IBS and bowel - disorder treatments such as antidepressants and mind - body therapies like cognitive behavioral therapy (CBT) and medical hypnotherapy.

Dr. Hammond's areas of interest include intracranial and spinal surgery as well as diagnosis and treatment of inflammatory disorders of the CNS.

Use with caution in animals with known or suspected Central Nervous System (CNS) disorders.

Key Highlights: • Conducted medical coding for clinical trials in therapeutic areas of pain management, infectious disease, inflammatory and autoimmune, respiratory, Psychiatry, CNS and metabolic disorders.