Sentences with phrase «ctl activity»

However, in vitro assays using spleen cells from CD4 KO mice that had rejected BALB / c corneal allografts failed to detect CTL activity against donor corneal epithelial or endothelial cells.

The results of a typical experiment are shown in Figure 3 and demonstrate that even though spleen cells from CD4 KO mice could adoptively transfer corneal allograft rejection, they did not display conventional CTL activity against either BALB / c corneal epithelial or endothelial cells.

However, this in vitro boosting culture protocol did not induce de novo CTL activity in cells from naïve mice.

However, findings published on August 14th in PLOS Pathogens now suggest that treatment with HDAC inhibitors might suppress CTL activity and therefore compromise the «kill» part of a two - pronged «flush - and - kill» HIV eradication strategy.

Not exact matches

In our study, CD8 − T cells from CD4 KO rejector mice failed to display CTL or DTH activity, yet they were capable of inducing donor - specific apoptosis of corneal endothelial cells.

Tumors can suppress CD4 + T cell activity and CTL tumor lysis directly through secretion of immunosuppressive factors including TGF - β1 but also PGE - 2, and IL - 10.

Product candidates generated from the GLAAS discovery platform are designed to amplify the anti-tumor activity of CTLs as well as other beneficial anti-tumor mechanisms.

Performed Inventory and Procurement oversight and assisted and trained all students in activities such as Plasmid Construction, Elutriation of Whole Blood, Dendritic Cell Studies, Organ / Tissue Processing, Ctl Assays, Cell Culture Maintenance, Transfection, Animal Handling, Flow Cytometry and Microscopy.