Sentences with phrase «cadherin by»
Dr. Islam's discovery was published [S. Islam, T. E. Carey, G. T. Wolf, M. J. Wheelock, and K. J. Johnson, «Expression of N - Cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell - cell adhesion,» J. Cell Biol.
http://www.sciencemag.org/ Not exact matches
The groundbreaking study identified a protein, known as cadherin - 22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.
He said that by collaborating with Indian scientists, «we discovered that the same cadherin gene is associated with the resistance in India, but the mutations are different and much more numerous than the ones we found in lab - selected pink bollworm from Arizona.»
Mutations that disrupt cadherin block this binding, which leaves the insect unscathed by the Bt toxin.
The researchers learned that the astonishing diversity of cadherin in pink bollworm from India is caused by alternative splicing, a novel mechanism of resistance that allows a single DNA sequence to code for many variants of a protein.
Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N - cadherin in rat liver epithelial cells.
Collagen I promotes metastasis in pancreatic cancer by activating c - Jun NH2 - terminal kinase 1 and up - regulating N - cadherin expression.
Cell division orientation is coupled to cell - cell adhesion by the E - cadherin / LGN complex.
N - Cadherin Dependent Collective Cell Invasion of Prostate Cancer Cells Is Regulated by the N - Terminus of α - Catenin.
CNRQ values were calculated by classic delta - delta - Ct method and normalized to the multiple housekeeping genes, cadherin - associated protein, beta 1 (CTNNB1) and GAPDH using the qBasePlus 1.3 analysis software.
By sequencing the DNA of resistant pink bollworm collected from the field in India — which grows the most Bt cotton of any country in the world — the team found that the insects produce remarkably diverse disrupted variants of cadherin.