«
Cancer test predicts treatment outcome.»
Not exact matches
The study, just published in Science, showed that the creation of what the researchers are calling microtumors can help
predict drug effectiveness in
cancer patients better than the current standard method of
testing the drugs on rodents.
LONDON, Oct 9 - Scientists have found two distinct genetic «signatures» for prostate
cancer that may help doctors
predict which patients have aggressive tumours, and designed experimental blood
tests to read those genetic signs like barcodes.
Can a Simple
Test Really
Predict Whether a
Cancer Treatment Will Succeed?
Source: Streetwise Reports (2/20/18) Imagine if a simple
test of a blood or tissue sample could
predict whether the standard treatment of care for a
cancer would be effective.
In October 2016, writing in Mathematical Models and Methods in Applied Sciences, the team used a study of
cancer in rats to
test 13 leading tumor growth models to determine which could
predict key quantities of interest relevant to survival, and the effects of various therapies.
Recent advances in the understanding of
cancer have led to more personalized therapies, such as drugs that target particular proteins and
tests that analyze gene expression patterns in tumors to
predict a patient's response to therapy.
The authors suggest that HAND2 methylation «could be applied to triage women who present with postmenopausal bleeding (currently ~ 90 % of women who present with this symptom and are
cancer - free must undergo endometrial biopsy for a definitive diagnosis) and could be further employed as a
test to early detect or even
predict the risk for endometrial
cancer and response to preventative treatment.»
Up until now, no single
test could
predict the severity of the
cancer type - the current PSA
test (Kallikrein 3), which is located near Kallikrein 6, only identifies the risk of prostate
cancer, not the severity.
Published in the journal
Cancer Research, the discovery has potential to lead to the development of a blood test that could predict whether cancer will spread from the prostate tumour to other parts of the
Cancer Research, the discovery has potential to lead to the development of a blood
test that could
predict whether
cancer will spread from the prostate tumour to other parts of the
cancer will spread from the prostate tumour to other parts of the body.
Seeing this microbe singlehandedly shift such a wide range of immune parameters calls for caution in interpreting personal DNA
tests that claim to
predict one's risk of a host of diseases from Alzheimer's to
cancer.
«The good news is that this finding
predicts that patients missing either gene should be sensitive to new therapies targeting focal adhesion enzymes, which are currently being
tested in early - stage clinical trials,» says Shaw, who is also a member of the Moores
Cancer Center and an adjunct professor at the University of California, San Diego.
Prostate
cancer is has a genetic component but it has until now been impossible to understand how aggressive the
cancer might be Now a new multi-national study has discovered the basis of a simple blood
test which can
predict whether a man is susceptible to aggressive prostate
cancer.
When
tested on various
cancer patient databases, iCAGES was found to be superior to other computational tools at
predicting cancer drivers from personal genomes and at identifying beneficial treatment.
Scientists are reporting a
test which can
predict which patients are most at risk from aggressive prostate
cancer, and whether they suffer an increased chance of treatment failure.
«Scientists report genetic
test to help
predict men at most risk from aggressive prostate
cancer.»
A personalized method for
testing the effectiveness of drugs that treat multiple myeloma may
predict quickly and more accurately the best treatments for individual patients with the bone marrow
cancer.
Clinical biochemist Eleftherios Diamandis of the University of Toronto in Canada
predicts that at least for initially diagnosing
cancer, the
tests may face an obstacle.
He now plans to
test whether the profiles of bacteria living in someone's gut can
predict how well they will respond to
cancer treatment.
Women with particularly aggressive forms of breast
cancer could be identified by a
test that
predicts whether the disease is likely to spread to the brain.
«New «mutation - tracking» blood
test could
predict breast
cancer relapse months in advance.»
«We have shown how a simple blood
test has the potential to accurately
predict which patients will relapse from breast
cancer, much earlier than we can currently.
A simple blood
test is currently in development that could help
predict the likelihood of a woman developing breast
cancer, even in the absence of a high - risk BRCA1 gene mutation, according to research published in the open access journal Genome Medicine.
«New
test predicts risk of non-hereditary breast
cancer.»
He
predicts that opportunities will expand for companies and academic labs that would like to do multiple - gene
testing for
cancer risk.
«We urgently need markers to
predict which therapies are going to be effective and which will not be effective in individual patients with advanced prostate
cancer,» said lead study author Emmanuel Antonarakis, MD, an assistant professor of oncology and urology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.&
cancer,» said lead study author Emmanuel Antonarakis, MD, an assistant professor of oncology and urology at the Sidney Kimmel Comprehensive
Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.&
Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7
testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.»
Gene expression profiling
tests, such as Oncotype Dx, analyze the patterns of 21 different genes within
cancer cells to help
predict how likely it is that a women's
cancer will recur within 10 years after initial treatment and how beneficial chemotherapy will be to her.
• A patient with blood
cancer who had received several diagnoses was found, through
testing, to have an unusual form of acute myeloid leukemia (AML), which
predicted responsiveness to imatinib.
Houston Methodist researchers led by Dario Marchetti, PhD, have developed a blood
test that can identify circulating tumor cells to
predict breast
cancer patients at risk for developing brain metastasis.
«Blood
test that detects changes in tumor DNA
predicts survival of women with advanced breast
cancer.»
In a 1988 paper summarizing his findings, Fiebig concluded that xenograft mice were wonderful models for broadly
testing new drugs against human tumors, but they «can not be used as a clinical routine method» for
predicting patient treatment.1 The idea of using xenograft mice as personal avatars for
cancer patients was discarded.
Previously, no
test existed to
predict whether people with the
cancer would respond to the treatment or not.
A new study has found a blood
test for
cancer DNA could
predict if a woman is responding to the new breast
cancer drug palbociclib, months earlier than current
tests.
The
test also
predicts which women are more likely to develop ER - positive breast
cancer if they develop
cancer at all.
The researchers
tested whether stromal tumor infiltrating lymphocytes (TILs) and other immune cells might
predict responses to therapy in a set of 30 HER2 - positive breast
cancer tissues treated with TCHP (26 patients) or with TCH without pertuzumab (4 patients).
Researchers are designing
tests that could
predict side effects of new
cancer treatments that boost our immune system.
PI3K inhibitors are the subject of some 100 clinical trials, including one that will
test whether a
cancer treatment's early failure to reduce glucose uptake, as measured by FDG PET, can
predict whether the therapy will fail to shrink a patient's tumor.
RPB researchers have developed a genetic
test that can accurately
predict whether the most common form of eye
cancer will spread to other parts of the body, particularly the liver.
12/8/2008 Interactive Gene «Networks» May
Predict if Leukemia is Aggressive or Slow - Growing Rather than
testing for individual marker genes or proteins, researchers at the University of California, San Diego (UC San Diego) and the Moores UCSD
Cancer Center have evidence that groups, or networks, of interactive genes may be more reliable in... More...
Genetic
testing also can reveal many that have unknown consequences for the function of these genes, so their influence on
cancer risk can't be
predicted.
In addition, our investigators have used epigenetic biomarkers to: develop screening
tests for
cancer; help guide surgeons in removing cancerous tumors;
predict drug resistance; and, pinpoint more aggressive
cancers.
deCODE believes the
test will be useful for better
predicting risk of prostate
cancer, helping to optimize both screening and treatment.
These include a
test to tailor breast
cancer tumor treatments, a noninvasive treatment to help paralyzed men gain movement, and a tool that may
predict suicide risk...
Dr. Amanda Paulovich of Fred Hutch has been selected to lead a multi-institution effort to develop a biological
test to
predict which treatments will work for patients with ovarian
cancer.