Scientists have linked BPA to a growing list of ailments: cancer, reproductive and
cardiovascular system disorders (including damage to the prostate gland, infertility and early puberty), brain and neurological system dysfunctions, behavioral problems, diabetes and obesity.
Not exact matches
Analysts point to three main therapeutic areas — cancer, central nervous
system disorders (such as Alzheimer's, depression and pain), and
cardiovascular disease — as core strengths of Canada's biopharmaceutical research industry.
This has been great for agricultural efficiency, but animal welfare activists have criticized the practice for creating birds that have major health issues due to their size, including leg
disorders, weakened immune
systems, and
cardiovascular problems.
Although far less common than
cardiovascular ailments and much less of a drain on the health - care
system, the hereditary
disorders identified so far are so well known to Finns that they are part of the lore of the nation.
Long - term sleep loss may affect the
cardiovascular, endocrine, immune and nervous
systems with severe consequences including hypertension, obesity and mental health
disorders, among others.
The MGH Research Institute conducts the largest hospital - based research program in the nation, with an annual research budget of more than $ 800 million and major research centers in HIV / AIDS,
cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative
disorders, regenerative medicine, reproductive biology,
systems biology, photomedicine and transplantation biology.
Annotations showed genes involved in gastrointestinal and neurological diseases; endocrine
system disorders; metabolism; perception; bone and limb morphogenesis; growth; and the development of the muscular,
cardiovascular, and nervous
systems.
Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation;
cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric
disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative
disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous
system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological
disorders Bart Staels, France - Nuclear receptor signaling in metabolic and
cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters
Despite the presence of the cell's antioxidant defense
system to counteract oxidative damage from ROS, oxidative damage accumulates during the life cycle and has been implicated in aging and age - dependent diseases such as
cardiovascular disease, cancer, neurodegenerative
disorders and other chronic conditions.
Extreme long - term endurance exercise can put a strain on the
cardiovascular system, ultimately placing you at risk of heart rhythm
disorders.
This damages the cells and eventually leads to complications such as diabetic retinopathy,
cardiovascular disorders, erectile dysfunction and
disorders of the nervous
system.
Disclaimer: Please consult with your physician before using Rosita EVCLO, or taking this product if you are pregnant or lactating, diabetic, allergic to fish or iodine, using blood thinners, anticipate surgery, have a diagnosed
cardiovascular condition, nutrient absorption issues, dealing with a chronic disease, bleeding or immune
system disorders.
Proanthozone is a potent antioxidant for adult dogs & cats for conditions linked to oxidative stress: compromised immune
system, liver & kidney disease, skin disease, pancreatic & G.I.
disorders,
cardiovascular disorders and degenerative joint disease.
Serious signs of panting in cats is a representation of a cat that is suffering from respiratory, hematological (blood related),
cardiovascular or nervous
system disorders.
Michelle Rose, DVM, DACVIM (Cardiology) and Robert George, DVM, DACVIM (Cardiology) are board - certified veterinary cardiologists dedicated to diagnosing, managing, and treating
disorders of the heart and
cardiovascular system.
They are dedicated to diagnosing, managing, and treating
disorders of the heart and
cardiovascular system.
«Age - related changes in cognitive functions, behaviour, skin, digestive tract,
cardiovascular system, respiratory tract, degenerative joint and skeletal function, as well as urinary
disorders are the most common issues concerning older dogs», explains Dr Brenten.
Immune
system degeneration, neurological
system disorders, cancer, arthritis, diabetes, multiple sclerosis, obesity,
cardiovascular disease, kidney failure, and even reproductive
system disorders, the list goes on and on.
The top five long - term disability claim diagnosis categories in 2014 were musculoskeletal / connective tissue, nervous
system related,
cardiovascular / circulatory, cancer and neoplasms, and mental
disorders.
One in four people suffer a disability before they retire, and most of the time, it's caused by a musculoskeletal
disorder, a nervous -
system issue,
cardiovascular disease, or cancer.