Sentences with phrase «cas9 gene modification»
«SapTrap, a Toolkit for High - Throughput CRISPR / Cas9 Gene Modification in Caenorhabditis elegans.»
http://blog.addgene.org/ Not exact matches
In 2016, for example, researchers reported that they had created a CRISPR / Cas9 gene drive that forces a fertility - reducing gene modification into female Anopheles gambiae mosquitoes — which could quickly reduce local Anopheles populations if unleashed in the wild.
With the advent of new, more efficient, and targeted gene - editing techniques such as CRISPR / Cas9, gene modifications can, in principle, be spread throughout a population of living organisms intentionally and quickly via a gene drive, circumventing traditional rules of inheritance and greatly increasing the odds that an altered gene spreads throughout a population.
The sequential processes of somatic cell reprogramming to create patient - specific hiPS cells, CRISPR / Cas9 gene editing, and single - cell cloning uniquely enable researchers to study how a specific genetic modification can influence function.
We also demonstrate the feasibility of Cas9 / gRNA - mediated multiple gene modifications in primary cells.
These findings encouraged us to explore the possibility of establishing a Cas9 / gRNA - based gene modification platform for large animals.