Gilead's deep dive into cellular therapeutics with the acquisitions of Kite Pharma and
Cell Design Labs, along with the subsequent licensing deal with Sangamo Therapeutics to develop off - the - shelf cell therapies, is another key value creator that's arguably being under - appreciated by the market.
Not exact matches
We hope this leads to the ability to
design, study and test new therapies for every patient on their own
cells in the
lab, leading to new treatments and breakthroughs in personalized medicine for individuals with a variety of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.
Synthetic biology, which involves
designing and building genetic constructs and testing them in living
cells, requires wet
lab skills.
The causes of such unpredictable results, Harris said, can include bad ingredients in the
lab, including contaminated and misidentified
cell lines; poor research
design, including insufficient numbers of mice in animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.
They geared their experimental
design towards conducting direct measurements in space: From thawing the test
cells to the measurements themselves, ESA astronaut Samantha Cristoforetti performed all the operations directly in the
lab on the ISS.
Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of
designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's
lab identified how microglia — a type of immune
cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.
Monoclonal antibodies are molecules, generated in the
lab, that are
designed to target cancer
cells and recruit immune
cells to attack.
His
lab has extensive experience evaluating and modulating T
cell responses to tumors and viruses, including introducing genes into T
cells to impart specificity and modulate function,
designing strategies to overcome tolerance and enhance in vivo activity, and developing mouse models that more accurately model human immune responses to candidate vaccines.
Fascinating research from the
lab of Mark Zylka, PhD, director of the UNC Neuroscience Center, suggests that chemicals
designed to protect crops can cause gene expression changes in mouse brain
cells.
, New British Art, MOCCA, Toronto (2013); LA Demeure Joyeuse, Galerie Franseca Pia, Zurich; London Open, Whitechapel Gallery, London; Material Maters, Courtauld Institute, London; Laying down and kissing the love in the mist, Kendall Koppe, Glasgow (all 2012); Slipped, Wysing Art Centre, Cambridge; Momentum, The Nordic Biennial, Moss; Collision, Museum of Art, Rhode Island School of
Design (all 2011); Newspeak: British Art Now, Saatchi Gallery, London; Das vertraute Unvertraute, Württembergischer Kunstverein Stuttgart (both 2010); Free Radicals, Arcade, London; Cabinet Afrique,
Cell Project Space, London (both 2009); Blue Balls, APF
LAB, New York; Soft Spot, 0047 OSLO, Oslo (both 2008); Amongst the Ashes and Millionaires, Ancient & Modern, London (2007).
Today's silicon crystal solar panels are a dramatic improvement over the original Bell
Lab designs, with some
cells achieving a conversion efficiency of about 35 %, but the power output is still intermittent and load factors are very low, around 15 %.
An international team, led by Berkeley
Lab scientists, has demonstrated a breakthrough in the
design and function of nanoparticles that could make solar panels more efficient by converting light usually missed by solar
cells into usable energy.
Both
designed by Facebook's Building 8 hardware
lab, Portal and Fiona will sport 15 - inch in -
cell touchscreen panels.
Co-manager, Pharma Biologics cGMP Analytical
Lab (PBAL)(1998 to 2000) Established (from design of structure and lab design) of cGMP bioassay laboratories (PBAL)- cGMP bioassay supervision and performance, and cGMP bioassay development Cell cultu
Lab (PBAL)(1998 to 2000) Established (from
design of structure and
lab design) of cGMP bioassay laboratories (PBAL)- cGMP bioassay supervision and performance, and cGMP bioassay development Cell cultu
lab design) of cGMP bioassay laboratories (PBAL)- cGMP bioassay supervision and performance, and cGMP bioassay development
Cell culture.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in
design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct
cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral
cell culture Working knowledge of
lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for
cell immobilization Formulated
cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated
cell and biomaterial interaction,
cell growth, and proliferation
Designed bench - top experiments and protocols to simulate in vivo situations
Designed hydrogel based microfluidic prototypes for
cell entrapment and
cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped
cells Evaluated intracellular and extracellular reactions of entrapped
cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies
Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign