Sentences with phrase «cell disease association»

She has also served with the Southern CT Sickle Cell Disease Association of America and was elected on the National Board for Sickle Cell Disease Association of America.

Memorials to the Greater Chicago Food Depository or Sickle Cell Disease Association, 231 E. Baltimore St., Suite 800, Baltimore, Maryland, 21202.

Not exact matches

Dr. Haywood's dissertation examined the association of patient - centered care with trust in the medical profession among adults with sickle cell disease.

Adipose - Derived Regenerative Cells Improve Cardiac Functional Capacity at 18 Months in Chronic Ischemic Heart Disease Patients; Statistically Significant Improvement in MVO2 Reported by Cytori at American Heart Association (November, 2010).

The focus is on molecular microbiology and virology, and includes topics such as genomics, the gamut of plant and animal host - pathogen interactions, host immune responses, characterization and evolution of virulence determinants, cell cycle and differentiation, symbiosis in plant and animal associations, environmental microbiology, biodiversity and evolution, population dynamics, sex and mutagenesis, antibiotic resistance and production, drug and vaccine targets, as well as aspects of prion diseases and of fungal and protozoan biology.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

These 45 variants are significantly enriched for protein - coding changes (n = 13), direct disruption of transcription - factor binding sites (n = 3), and tissue - specific epigenetic marks (n = 10), with the last category showing enrichment in specific immune cells among associations stronger in Crohn's disease and in gut mucosa among associations stronger in ulcerative colitis.

In the original identification of XMRV in prostate cancer stromal cells, Urisman et al. [3] confirmed by sequence analysis that XMRV is not a laboratory contaminant, as is often the case with claims of new retroviral associations with disease.

Having higher BDNF stimulates the growth of new brain cells in the brain's memory center and is associated with a dramatic reduction in the risk for Alzheimer's disease as was recently reported in the Journal of the American Medical Association.

The association between canine diabetes and pancreatitis warrants particular attention, because β - cell autoimmunity, pancreatic inflammation, and regulation of gut immunity may be linked in disease pathogenesis.

An understanding of the genetic basis of variability of these cells and proteins, and of the association of this variability with a variety of diseases that commonly affect cats, including diabetes, has the potential to dramatically improve the diagnosis and treatment of cats with these conditions.

According to the ALS Association, ALS or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord.

Further investigation of the association of caregiver appraisals and family functioning is warranted with the goal of addressing the stress that disease management with sickle cell may add to parent — child relationships.