Sentences with phrase «cell immunoglobulin»

KIRs (or killer cell immunoglobulin - like receptors) are found on the surface of natural killer (NK) cells.

Parham P. Killer cell immunoglobulin - like receptor diversity: balancing signals in the natural killer cell response.

Amsbio announces a suite of high quality proteins and biotinylated proteins for research into killer - cell immunoglobulin - like receptors

Not exact matches

** The immunological defense system of the soft mucosa, which may produce antibacterial and antiviral proteins such as lysozyme, also found in mothers milk, and plasma cells, which secrete immunoglobulin antibodies.

They are cells or immunoglobulin that help to build the baby immune system.

It contains antioxidants, immune cells, growth factors, immunoglobulins.

Babies are fed large amounts of immune cells, such as leukocytes, and antibodies called secretory immunoglobulin A (IgA) passed from the mother to help fight against many harmful agents.

This rich substance contains vital ingredients, including immunoglobulin or cells that help build your baby's immune system.

Colostrum consists of high concentrations of immunoglobulins, maternal antibodies that protect your baby's immune system, as well as white blood cells, water, protein, fat, minerals, vitamins and carbs.

Colostrum contains high concentrations of secretory IgA, the predominant immunoglobulin passed through your breast milk, lactoferrin, which acts as an antibacterial to prevent infection in human infants, and leukocytes, protective white cells.

A viral epitope inserted into the complementarity - determining region 3 (CDR3) loop of the heavy chain of a self immunoglobulin (Ig) molecule was generated from the Ig context and was presented by I - Ed class II molecules to virus - specific, CD4 + T cells.

By using engineered zinc - finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a high frequency of animals carrying 25 to 100 % disruption at the target locus.

Immunoglobulin G (IgG) antibodies from patients with the syndrome, applied to bovine adrenal chromaffin cells, reduced the voltage - dependent calcium channel currents by about 40 percent.

She found «an increase in IgA -[immunoglobulin --RSB- producing B cells in both the colon and the lymph nodes» as well as an increase in T helper cells in the lymph nodes.

The researchers also found that treating the mice with a molecule called CTL - associated antigen - 4 immunoglobulin (CTLA4Ig) suppressed damage to liver cells infected with hepatitis B virus, suggesting that this might be a potential approach to treatment.

Porter will also monitor the patients» long - term health; since they lack healthy B cells, they may require lifelong immunoglobulin to help resist other cancers, immune disorders, and infectious disease.

In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of toxic abnormal immunoglobulin called monoclonal protein that can damage multiple organs.

There it passes on the fragments to other immune cells, which produce a distinctive fork - shaped antibody, known as immunoglobulin E, or IgE.

The apCAM's are members of the immunoglobulin class of cell adhesion molecules and resemble two neural cell adhesion molecules, NCAM and fasciclin II.

But rather than delivering the entire gene for the clotting - factor proteins to cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B cells to express a fragment of the clotting factor fused to an immune molecule called an immunoglobulin.

Two types of immature B cells, namely fetal liver hybridomas and the leukemic cell line 70Z / 3, both of which have cytoplasmic mu chains but no light chains, were examined for DNA rearrangements of their light chain and heavy chain immunoglobulin genes.

The results suggest that, although the lack of light chain synthesis can be due to a lack of gene rearrangement, there may also be transcriptional regulation, which may also be important for the expression of light chain immunoglobulins in immature B cells.

S. mansoni IPSE binds to Immunoglobulin E (IgE), an antibody produced by the immune system that is expressed on the surface of basophils, a type of immune cell; and mast cells, another immune cell that mediates inflammation; and sequesters chemokines, signaling proteins that alert white cells to infection sites.

This research dealt with the question of how IgA could cross a cell layer by binding to polymeric immunoglobulin receptors (pIgR).

Since B cells play a role in helping fight infection, patients typically receive immunoglobulin replacement to maintain healthy immune function.

They also rally forces by docking to the CD40 receptor of B cells, stimulating these cells to manufacture potent immunoglobulin G (IgG) antibodies that can inactivate foreign proteins.

When you come into contact with an allergen — ragweed, for example — immunoglobulin E (IgE) specific to that allergen acts through its receptor on the mast cell, stimulating the mast cells and basophils to release mediators, such as histamine, that trigger an allergic response.

Toll - like receptor 9 - dependent and - independent dendritic cell activation by chromatin — immunoglobulin G complexes.

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

Gross G, Waks T, Eshhar Z. Expression of immunoglobulin - T - cell receptor chimeric molecules as functional receptors with antibody - type specificity (chimeric genes / antibody variable region).

Bogen B. Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4 + T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma.

Analysis of homozygous mutant chimeric mice: deletion of the immunoglobulin heavy - chain joining region blocks B - cell development and antibody production.

Tatsiana Audzevich (Jessberger, TUD)-- «The function of SWP - 70 in CD40 / IL -4 induced beta cell activation and immunoglobulin E class switch recombination» (2009)

Activation and tolerance in CD4 + T cells reactive to an immunoglobulin variable region.

«Although molecules such as FcRn do function in the immune system, in that they transport immunoglobulin, they certainly don't present antigens to T cell receptors, the primary function of MHC proteins,» said Bjorkman.

Fab fragments can be used to block endogenous immunoglobulins on cells, tissue, or other surfaces, and to block the exposed immunoglobulins in multiple labeling experiments using primary antibodies from the same species.

IgDiscover uncovers genetic diversity in the immunoglobulin loci at the individual level, enabling an improved understanding of protective and pathogenic B cell responses in a variety of settings and facilitating future personalized immunization strategies.

BIOMED - 2 multiplex immunoglobulin / T - cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics.

In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell - based model of AL amyloidosis

Michael's image shows COS - 7 cells ectopically expressing the Fcγ - receptor performing phagocytosis on beads opsonised with Immunoglobulin G. His false - colour scanning electron micrograph shows filopodia and pseudopodia projecting around the beads, which will subsequently be fully engulfed.

The antigen receptor genes that undergo rearrangements are the immunoglobulin heavy chain (IGH) and light chain loci (IGK and IGL) in B cells, and the T cell receptor gene loci (TRA, TRB, TRG and TRD) in T cells.

Other studies have shown that a family of proteins called 14 -3-3 are involved in learning along with interesting cell adhesion molecules of the integrin family and the immunoglobulin superfamily.

The antibodies used in this study includes COX - 2 (Cayman Chemicals, Ann Arbor, MI, USA), STAT6 for Western blot (Cell Signaling Technology, Danvers, MA, USA), for immunofluorescence (IF)(BD Pharmingen, San Diego, CA, USA), for ChIP (Santa Cruz Biotechnology, Santa Cruz, CA, USA), phospho - STAT6 (Cell Signaling Technology), p300 for Western blot, (Upstate, Lake Placid, NY, USA), for ChIP (Santa Cruz Biotechnology), normal rabbit IgG (Santa Cruz Biotechnology), mouse immunoglobulin (Ig) G1, κ Ig (BD Pharmingen), glyceraldehyde -3-phosphate dehydrogenase (Advanced ImmunoChemical, Long Beach, CA, USA), Cy3 - conjugated AffiniPure Goat anti-mouse IgG (Jackson ImmunoResearch, West Grove, PA, USA) and PARP (Cell Signaling Technology).

Nodal Involvement By Marginal Zone B - Cell Lymphoma Harboring t (14; 22)(q32; q11) Involving Immunoglobulin Heavy Chain and Light Chain Lambda as the Sole Karyotypically Recognizable Abnormality in a...

The laboratories also offer highly sensitive NGS - based MRD assays to track FLT3 mutations and patient - specific immunoglobulin and T - cell receptor gene rearrangements.

The diagnostic domains of two major cell — cell adhesion superfamilies, the cadherins and the immunoglobulins, are present in Monosiga within the extracellular region of putative transmembrane proteins31, 34 (Supplementary Note 8.8).

Developing B cells use somatic hypermutation (SHM) to diversify their immunoglobulin (Ig) genes.

Noncoding transcripts originating upstream of the immunoglobulin constant region (I transcripts) are required to direct activation - induced deaminase to initiate class switching in B cells.

In contrast, we did not detect any human immunoglobulin bound to the surface of neighboring MCF7 cells (Fig. 2A).

We also demonstrate that immunoglobulin - secreting NSCs exhibit preferential tropism to tumor cells in vivo, and can deliver antibodies to human breast cancer xenografts in mice.