Sentences with phrase «cell metabolism showed»

A companion study published by the Buck Institute for Research on Aging in the same issue of Cell Metabolism shows that a ketogenic diet extends longevity and improves memory in aging mice.

Not exact matches

Choline's benefits are not just limited to maternal and infant health, and research shows that choline plays a critical role in cell membrane signaling, helps to regulate metabolism, and promotes liver and cardiac health across the lifespan.1

The results show that foods may reprogramme our DNA (Cell Metabolism, DOI: 10.1016 / j.cmet.2009.07.011).

Researchers showed that flu infection changed the metabolism of human lung epithelial cells, the prime location for replication of flu virus.

The findings, which will be published April 28 in Cell Metabolism, highlight the importance of two genes not previously implicated directly in pancreatic function, and show that the pancreas continues to develop and mature during the first decades of life.

In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body).

According to Bolton, 8 - PN showed only a slight increase of metabolism in breast cells, while the other two compounds did not have significant effects in either cell line.

Further analysis showed that wild type HIV - 1 tends to integrate itself into or near genes affecting CD4 + T cell activation and metabolism more frequently than does the mutant strain.

Moreover, when induced to differentiate into amastigotes extracellularly, in host cell - free culture, the parasites with reduced LMIT1 function showed incomplete differentiation and severe defects in iron content and iron - dependent mitochondrial metabolism.

The structure of this complex, determined using cryo - electron microscopy, shows how it converts near - infrared light into an electrical charge in order to power cell metabolism, which enables this bacterium to live at the extreme red limit of photosynthesis on Earth.

Further research showed that the WWOX gene plays a role in the altered metabolism of cancer cells which are known to use glucose differently to normal cells.

«This study breaks new ground because it focuses on boosting beta cell performance and shows that beta cell preservation is possible even in the face of such immune attack,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and J.S. Simmons Professor of Genetics and Metabolism at HSPH.

Here, we exploited microfluidics to control the metabolism of liver cells down to a resolution of a few cells, allowing us to create liver tissue that shows the same patterns of toxicity caused by differences in drug metabolism as the liver in your body.»

In Cell Metabolism on August 13, the Harvard scientists who discovered irisin address this contentious issue by showing that human irisin circulates in the blood at nanogram levels and increases during exercise.

The Altieri lab showed that the protein Akt, which plays a key role in cell signaling and metabolism, accumulates in mitochondria during hypoxia.

In a paper published August 13 in Cell Metabolism, the researchers show how, contrary to popular claims, restricting dietary fat can lead to greater body fat loss than carb restriction, even though a low - carb diet reduces insulin and increases fat burning.

«Additionally, we showed that obesity increases the number and activity of NK cells in abdominal fat but not in other tissues,» says Lee, senior author on a paper published online in Cell Metabolism.

Cancer cells are well - known as voracious energy consumers, but even veteran cancer - metabolism researcher Deepak Nagrath was surprised by their latest exploit: Experiments in his lab at Rice University show that some cancer cells get 30 - 60 percent of their fuel from eating their neighbors» «words.»

Here we show that these cells exhibit decreased mRNA levels for additional genes contributing to telomere metabolism, but also, surprisingly, for 12 genes mutated in Fanconi anaemia.

These findings show that regulation of retinoid metabolism and signaling is part of PPARγ - controlled events in these cells.

They further show that, by regulating lipid metabolism, a cell is able to switch its immune phenotype by using transcriptional mechanisms and that the lipid environment has an important impact on immune cell function.

Studies in cells and genetically modified mice show that the regulatory subunit of the PI 3 - kinase, a protein called p85, works both ways, says C. Ronald Kahn, M.D., Head of the Joslin Section on Integrative Physiology and Metabolism, and senior author on a Nature Medicine paper reporting the discovery on March 28.

«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune cells change during cardiovascular disease progression in humans,» says Hedrick.

«We show that Sirt4 is responsible for regulating both lifespan and metabolism in an organism, and specifically that it coordinates the metabolic response to fasting,» said lead author Jason Wood, a researcher in Brown University's Department of Molecular Biology, Cell Biology and Biochemistry.

Here, we show that enhanced hiPS - HEP cells respond to insulin with phosphorylation of protein kinase B - α (Akt), even at low insulin concentrations (Figure 4, Panels E and F), and that the genes involved in glycogen metabolism, gluconeogenesis, and insulin signaling are expressed at similar levels as in hphep cells (Figure 4, Panels B, C, and D).

We showed that a chronic oxidative stress accelerates aging through accumulation of HIF (Hypoxia - Inducible Factor) and modulation of insulin signaling (Gerald, Cell, 2004; Laurent, Cell Metabolism, 2008).

«The present study fills a gap in the literature by showing the relationship between the fatty acid metabolism and the migration of endothelial cells.»

«This finding is very new and very important, because it shows us the role of cellular metabolism in how these immune cells function.»

Studies have shown that CLA not only helps you drop fat, by reducing the amount of fat stored in your fat cells, but it also boosts your metabolism.

Research shows that pollutants from pesticides can be stored in your fat cells; this can cause a dip in your metabolism.

Raspberries • The metabolism in our fat cells can be increased by the phytonutrients found in raspberries • Recent research shows that organic raspberries are significantly higher in total antioxidant capacity than non organic.

Besides the many health benefits (reduction of bah cholesterol, reduction of high blood pressure etc.) it has, research has shown that the active substance EGCG in green tea can also increase your metabolism by 4 % in 24 hours and stop the movement of glucose into fat cells.

Not only do hydrated cells and body parts use energy better (making you less likely to want to eat) but icy H20 has been shown to bring your metabolism up by about 50 a day (5 lbs a year).

It has been thoroughly researched and shown that the overall health of a body is intrinsically linked to the health of its cells and their ability to metabolize oxidation.5 When oxidative metabolism's limits are exceeded free radicals and reactive oxygen species (ROS) are created and start to build up within the body.

Several studies have shown that people with schizophrenia often have low levels of the particular EFAs necessary for normal nerve cell membrane metabolism.

The component in buckwheat responsible for its blood glucose - lowering effects appears to be chiro - inositol, a compound that has been shown in other animal and human studies to play a significant role in glucose metabolism and cell signaling.

Studies show that it stimulates enzyme systems, cell metabolism, circulation and collagen formation.

Research published in 2013 in Science Translational Medicine shows that silver, in the form of dissolved ions, attacks bacterial cells in two ways: making the cell membrane more permeable, and interfering with the cell's metabolism.

It has been shown to interrupt glucose metabolism at a fundamental level and inhibit the expression of various kinases, which stimulate cancerous activity in the cells.

Research shows that alpha lipoic acid alleviates symptoms of diabetic neuropathy, including cardiac autonomic neuropathy, by improving blood flow to nerve cells and energy metabolism in nerve cells.

Furthermore, CBD and another component of marijuana, tetrahydrocannabivarin (THCV), may reduce body weight, as animal models of obesity using overweight mice have shown THCV to increase metabolism of fat cells.

Namely, cancer cells have been shown to exhibit an altered metabolism.

Furthermore, high blood levels of insulin can act by increasing androgenous hormonal stimulation of the ovarian theca cells as well as potentiating gonadotropin - stimulated ovarian androgen steroidogenesis — although recent data has suggested that the insulin - induced increase in ovarian hormone secretion is not accompanied by increased steroid metabolism.74 Hyperinsulinaemia may also affect the central actions of androgen by impairing progesterone inhibition of the gonadotropin - releasing hormone pulse generator.75 Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hormone.76

More recently, «studies have shown that D3 can help activate hair growth by similar means — boosting the metabolism of the follicles and encouraging those cells to turn over in a more normal way,» says Michelle Henry, MD, a dermatologist in New York City.

the regions expected to have the greater absorption of RF - EMFs from the cell phone exposure were the ones that showed the larger increases in glucose metabolism.

A PET scan, which stands for Position Emission Tomography (it looks at glucose metabolism), is used to show how the cells use glucose, as an indication of brain injury or a marker for brain injury.