Mehlhaff CJ, Peterson ME, Patnaik AK, Carrillo JM: Insulin producing islet
cell neoplasms: Surgical considerations and general management in 35 dogs.
Multiple myeloma and other plasma
cell neoplasms (cancers) are diseases in which the body makes too many plasma cells.
Bortezomib, carfilzomib, and ixazomib are proteasome inhibitors used in the treatment of multiple myeloma and other plasma
cell neoplasms.
Daratumumab and elotuzumab are monoclonal antibodies used in the treatment of multiple myeloma and other plasma
cell neoplasms.
The following types of plasma
cell neoplasms are cancer:
Plasma
cell neoplasms are most common in people who are middle aged or older.
For more information from the National Cancer Institute about multiple myeloma and other plasma
cell neoplasms, see the following:
Panobinostat is an HDAC inhibitor used in the treatment of multiple myeloma and other plasma
cell neoplasms.
Plasma
cell neoplasms are diseases in which abnormal plasma cells or myeloma cells form tumors in the bones or soft tissues of the body.
Several types of targeted therapy may be used to treat multiple myeloma and other plasma
cell neoplasms.
Supportive care is given to treat problems caused by multiple myeloma and other plasma
cell neoplasms.
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma
cell neoplasms and late - stage differentiation of normal B cells.
Mice have a high incidence of Hodgkin's - like reticulum
cell neoplasm at 18 months of age and pituitary tumors in old multiparous females.
«Remissions of Acute Myeloid Leukemia and Blastic Plasmacytoid Dendritic
Cell Neoplasm Following Treatment with CD123 - Specific CAR T Cells: A First - in - Human Clinical Trial» is presented at the ASH Annual Meeting Dec. 9 to 12, 2017.
Blastic plasmacytoid dendritic
cell neoplasm (BPDCN) is a very aggressive type of cancer with multiple manifestations including skin lesions, abnormal cell counts and central nervous system (CNS) disease involvement.
In this type of plasma
cell neoplasm, less than 10 % of the bone marrow is made up of abnormal plasma cells and there is no cancer.
Not exact matches
Once triggered, the «subroutine» of cancer results in a
neoplasm (a group of new, cancerous
cells) becoming mobile; this is metastasis, responsible for most deaths from cancer.
The SC3 tool was then used to analyse single -
cell RNA - sequence data from two patients diagnosed with myeloproliferative
neoplasm (MPN) blood cancers.
Myeloproliferative
neoplasms (MPN) are diagnosed in around 3,300 UK patients every year and cause an overproduction of blood
cells creating a significant impact on quality - of - life, with symptoms such as night sweats, itching and tiredness.
Primary osteosarcomas of the skull are aggressive
neoplasms composed of spindle
cells producing osteoid which have poor outcome.
We screened the coding sequences of 518 protein kinases (approximately 1.3 Mb of DNA per sample) for somatic mutations in 26 primary lung
neoplasms and seven lung cancer
cell lines.
Type II EATL (Epitheliotropic Intestinal T -
Cell Lymphoma): A
Neoplasm of Intra-Epithelial T -
Cells with Predominant CD8aa Phenotype.
In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative
neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T -
cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10
Myeloproliferative
neoplasms (MPNs) are blood disorders in which the bone marrow makes too many of one or more types of blood
cells — white blood
cells, red blood
cells or platelets.
Myeloproliferative
neoplasms are a group of rare disorders of the bone marrow that cause an increase in the number of blood
cells.
Myeloproliferative
neoplasms (MPNs) are a group of related clonal hemopoietic stem
cell disorders associated with hyperproliferation of myeloid
cells.
pigmentary disorders (melasma), infection (warts), hair loss, and even
neoplasms (basal
cell carcinoma).
The most common cause of obstruction is a urethral plug, which consists of mineral crystals (e.g., struvite, calcium oxalate), white blood
cells, red blood
cells, protein (mucus), and epithelial
cells.5 The underlying cause of urethral plugs is unknown; however, plugs have been linked to struvite crystalluria — suggesting that diet may play a role — and idiopathic cystitis.6 Other causes of urethral obstruction include urethral edema and spasm associated with lower urinary tract inflammation and pain.7 Uroliths,
neoplasms, and urethral strictures can also lead to urethral obstruction; however, they are reported less frequently than other causes.5
Any malignancy will be diagnosed with a
cell biopsy, with most
neoplasms found to be cancerous.
These are anaplastic (undifferentiated
cell, characteristic of malignant
neoplasms) round
cells that no longer resemble macrophages (white blood
cells within tissues, produced by the division of monocytes) and display multiple criteria for malignancy.
The cancer is in the form of a tumor (also called a
neoplasm which means abnormal
cell growth).
These tumors (also called mastocytomas, mast
cell sarcomas) are the most frequently recognized malignant or potentially malignant
neoplasms of dogs.
Sertoli - Leydig
cell tumors are members of the sex cord gonadal stromal tumor groups (tumors of sex cord derived tissues) of ovarian
neoplasm.
This a rare condition in which the adrenal gland suffers from abnormal
cell growth such as tumor or what is referred to as a
neoplasm.
Thymoma is an uncommon canine and feline
neoplasm of thymic epithelial
cells.
Skin tumors are the most commonly diagnosed
neoplasms in veterinary medicine.2 These
neoplasms represent a diverse group of benign and malignant growths arising from a variety of
cell types.
Infections, Calculi (forms into cat bladder stones) and
Neoplasms (abnormal
cell growth such as cancer) in the bladder are the main cat bladder problems.
When a dog's body has cancer, the
neoplasms (cancer
cells) are fueled by simple sugars or glucose (glycosis).
Lymphoma accounts for nearly 25 % of all canine
neoplasms, and 60 - 80 % of these are of B -
cell origin.