«Techniques like this tend to have a democratizing effect,» opening up opportunities for smaller groups, Molly Maleckar, the director of mathematical modeling at the Allen Institute for
Cell Science who was not involved in the study, tells Wired.
Not exact matches
Unlike most other philosophers of
science, he does not immediately cast scorn on the likes of William Dembski and Michael Behe,
who have focused on the apparent design of
cells and organisms.
The ANT - OAR proposal represent a scientifically and morally sound means of obtaining human pluripotent stem
cells that does not compromise either the
science or the deeply held moral convictions of those
who oppose the destructive use of human embryos for research» which is a creative approach that can be embraced by both the anything - goes camp and the nothing - goes.
«Once this novel tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse for paclitaxel, carrying the drug inside the cancel
cell, killing the
cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical
sciences at UCR's School of Medicine
who led the research.
The German - born Frank,
who was inducted as a AAAS fellow in 1997, is a professor of biochemistry, molecular biophysics and biological
sciences at Columbia in New York City and the Scottish - born Henderson,
who has been a AAAS member since 1996, has served as director of the MRC Laboratory of Molecular Biology research facility where hundreds of scientists work on neurobiology,
cell biology and biotechnology.
Speeches came from a variety of speakers, including a
science broadcaster and writer, a Pakistani - born Canadian Muslim
who works in STEM, a Pakistani - born professor
who studies
cell biology and anatomy; and, an emergency room physician
who helped start the process to phase out coal - fueled power plants by 2030 in Alberta.
«The discovery of the microbiome and its significance represents a huge paradigm shift in our understanding of human health — there are more microbes living on us and in us than our own
cells,» said Ingber,
who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children's Hospital, and Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied
Science.
The elusive e-mailers,
who claim to be part of a group called the Stem
Cell Research Watch Group, responded to an e-mail from
Science saying that they are «a group of students majoring in biology and often discuss papers that are taught in class.»
Also look at the institution's broader scientific environment, because «you can benefit from help even from people that are not with the label «biomaterials,»» says Dupont - Gillain,
who, as a bioengineer and physical chemist, collaborates with colleagues in surface
science and
cell biologists to develop biomimetic surfaces that can trigger desired
cell behaviors.
The paper's lead author — Marcus Yip,
who completed his PhD at MIT last fall — and his colleagues Rui Jin and Nathan Ickes, both in MIT's Department of Electrical Engineering and Computer
Science, will also exhibit a prototype charger that plugs into an ordinary
cell phone and can recharge the signal - processing chip in roughly two minutes.
In
science news around the world, scientists march in India to call for more research funding, a South Korean researcher
who was enmeshed in a stem
cell scandal a decade ago resigns from a newly created government position, Canada establishes a vast marine conservation area in the High Arctic, a highly regarded advocate for
science is convicted of financial misdemeanors in Egypt, and more.
Who We Are As Scientists 6 October 2006 Spurred by the stem -
cell scandal, a group of Korean early - career scientists organized an international conference on ethical issues in
science.
The two proteins have different biochemical properties and recognize different DNA sequences, so these properties create more options for gene - editing,» said Dr. Olson,
who holds the Pogue Distinguished Chair in Research on Cardiac Birth Defects, the Robert A. Welch Distinguished Chair in
Science, and the Annie and Willie Nelson Professorship in Stem
Cell Research.
Dr Lee Campbell, Research Projects and
Science Communications Manager at Cancer Research Wales,
who part - fund the study, commented: «This is an exciting breakthrough as cancer stem
cells are thought to be responsible for the failure of many cancer treatments and the re-emergence of cancers, often many years after the initial disease.
Unlike humans,
who use their lymphatic systems to produce and transport white blood
cells, tuna use theirs to move two of their fins, researchers report today in
Science.
25 October 2013: The 2013 Nobel Laureates
who published in
Science include, for Medicine, James E. Rothman, Randy W. Schekman and Thomas C. Südhof for their discoveries of machinery regulating vesicle traffic, a major transport system in our
cells.
Robert Hockaday,
who founded Energy Related Devices, a company working on fuel
cells in Los Alamos, New Mexico, told
Science magazine that the material «could set a new gold standard.»
At its heart, scientific editing is still about publishing a field's most interesting and influential papers, which means that reading, writing, and thinking about
science are still at the core of the job, says
Cell Stem
Cell editor Deborah Sweet,
who is based in Cambridge, Massachusetts.
«Our Premier Scholarships are aimed at bright students
who are preparing to undertake a Ph.D. in the area of stem
cell science,» Livesey says.
«Dermal papilla
cells give rise to hair follicles, and the notion of cloning hair follicles using inductive dermal papilla
cells has been around for 40 years or so,» said co-study leader Colin Jahoda, PhD, professor of stem
cell sciences at Durham University, England, and co-director of North East England Stem Cell Institute, who is one of the early founders of the fi
cell sciences at Durham University, England, and co-director of North East England Stem
Cell Institute, who is one of the early founders of the fi
Cell Institute,
who is one of the early founders of the field.
However, only rigorous
science and responsible regulation can ensure the safe and effective translation of
science into effective therapies,» remarked Paolo Bianco, Pathologist, Stem
Cell Biologist, Professor of Pathology at the University of Roma «La Sapienza» and one of the 13 authors of the commentary
who come from Italy, Germany, the United Kingdom, The Netherlands and the United States.
«The long - term vision is simple,» said Saif,
who is also part of the Beckman Institute for Advanced
Science and Technology at the U. of I. «Could we make elementary structures and seed them with stem
cells that would differentiate into smart structures to deliver drugs, perform minimally invasive surgery or target cancer?»
I might as well hire someone
who demonstrated the interest and tenacity to stay in
science,» says Bob van de Water, a molecular
cell biologist at Leiden University.
Chun - Chao Chen, a graduate student in the UCLA materials
science and engineering department
who is the paper's primary author, said using transparent and semi-transparent
cells together increases the device's efficiency, and that the materials were processed at low temperatures, making them relatively easy to manufacture.
«This development has the potential to enable earlier detection of solid tumors through a simple blood draw by substantially improving our ability to detect very low quantities of circulating DNA derived from tumor
cells,» says corresponding author Hunter Underhill, M.D., Ph.D.,
who initiated the research while in the lab of senior author Jay Shendure, M.D., Ph.D., a professor in genome
sciences at the University of Washington.
«Compared to any other device that converts chemical energy into electricity, the fuel
cell, and in particular the solid oxide or ceramic fuel
cell, is hands down the most efficient,» says veteran fuel
cell researcher Eric Wachsman, director of the University of Maryland Energy Research Center,
who published research pointing the way to lower temperature SOFCs on November 18 in
Science.
Michael Sandel, a Harvard professor of political
science who served for four years on President Bush's bioethics panel, said the committee's prolonged discussion of alternative methods of isolating embryonic stem
cells could be viewed as an effort to diminish public support for the research.
After my meeting with Rajesh,
who impressed me and is now in line to do the same with my client, I met Susan, a
cell biologist whose career in
science has been driven just as surely by passion as Rajesh's was.
«Although there are advantages to living in cities, such as the access to food, they seem to be outweighed by the disadvantages, such as stress — at least in terms of how quickly the
cells of the great tits age,» says biologist Pablo Salmón
who conducts research in the field of evolutionary ecology at the Faculty of
Science, Lund University.
But Vivek Malhotra, an American
who spent 18 years at the University of California, San Diego and is now the Coordinator of the
Cell and Developmental Biology Programme at CRG and a professor at ICREA, clarifies that when it comes to enjoying the Spanish lifestyle of
science, it really is a matter of where you go.
Michael Eisenbach and Martin Welch
who work at the Weizmann Institute of
Science in Rehovot, Israel, and Kenji Oosawa and Shin - Ichi Aizawa of Teikyo University in Japan, have studied a bacterium that has between 6 and 12 flagella spread randomly over the
cell surface.
But while researchers have previously been able to infect cultures of human hepatocytes with HBV, the
cells» limited lifespan has made it difficult to study the virus, says Bhatia,
who is also a Howard Hughes Medical Institute investigator and a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and
Science.
Professor Bowles,
who referred to the research in a panel discussion on «Nature's Marvellous Medicines» at the recent Royal Society Summer
Science Exhibition, said: «We were measuring how flavonoids affected the production of inflammatory mediators by
cells stimulated by microbial products.
After discussing the idea with Doudna, they floated the concept by two key CRISPR researchers in Cambridge, Massachusetts: George Church at Harvard University and his former postdoc Feng Zhang of the Broad Institute,
who had just published their own widely noticed
Science papers showing that the CRISPR system could guide its bacterial enzyme, Cas9, to precisely target and cut DNA in human
cells.
«In the traditional
science track, you learn to do one thing very well, but there's no real opportunity to develop teaching skills,» explains Bockholt,
who «turned down faculty positions and took the job at
CELL to really broaden my skills... skills that I couldn't get in a research position.»
«This is a significant example of how knowing details of potential mechanisms and the basic
science of redox active compounds in cancer versus normal
cells can be leveraged clinically in cancer therapy,» says co-senior author Douglas Spitz,
who focused on the biochemical studies.
But the win was also a hopeful sign for scientists
who have watched from the sidelines in disbelief as politicians cut
science funding and distorted research on evolution, stem
cells and global warming.
However, much of this work is still in its nascent stages,» said Binghamton University Electrical and Computer
Science Assistant Professor Seokheun Choi,
who is one of the co-authors of «Self - sustaining, solar - driven bioelectricity generation in micro-sized microbial fuel
cell using co-culture of heterotrophic and photosynthetic bacteria,» along with PhD candidate Lin Liu.
In 2006, Woo Suk Hwang had to retract two papers published in
Science in which his team claimed it had used the technique employed in cloning Dolly the sheep to create human embryonic stem
cells matched to specific people
who had various diseases.
The researchers were led by P. Michael Conn, Ph.D.,
who was a senior scientist in reproductive
sciences and neuroscience at OHSU's Oregon National Primate Research Center and professor of physiology and pharmacology,
cell biology and development and obstetrics and gynecology at OHSU for the past 19 years.
«We would argue that whatever happens in the human body is going to be quite efficient, quite rapid,» said University of Illinois
cell and developmental biology professor Fei Wang,
who led the study with visiting scholar Qiuhao Qu and materials
science and engineering professor Jianjun Cheng.
«It brings closure to the whole story,» says Jose Cibelli of Michigan State University in East Lansing,
who has derived stem
cells from monkey parthenotes (
Science, 1 February 2002, p. 819) and
who at one point advised Hwang on how to distinguish a parthenote from a clone.
Converting adult skin
cells into pluripotent
cells — immature stem
cells that can be programmed to become any tissue in the body — is a rapidly developing area of
science that earned the researcher
who discovered the technique, Shinya Yamanaka, a Nobel Prize in 2012.
Zhang,
who earned an M.D. from the Peking University Health
Science Center in China and a Ph.D. from the National University of Singapore, was recruited in 2007 to the Texas team that expected to see an increase of brain metastasis when PTEN, a known tumor - inhibiting protein, was artificially deleted in a tumor
cell.
Other co-authors on the study include James Bullock, a Berkeley Lab postdoctoral researcher in materials
sciences,
who was instrumental in engineering the system's photovoltaic and electrolysis
cell pairing.
The procedure was pioneered by Shoukhrat Mitalipov, a researcher at Oregon Health and
Science University
who focuses on early embryo development and stem
cell biology.
Liron Bar - Peled and Lynne Chantranupong,
who are both authors of the
Science article and graduate students in Sabatini's lab, found that GATOR1 itself is mutated in several cancers, including glioblastomas and ovarian cancers, and that cancer
cells with these mutations are also highly sensitive to treatment with rapamycin.
«This is important biotechnologically, because if you look at if from the angle of genome editing, the delivery of small genes into
cells is much easier than the delivery of large genes,» said Rotem Sorek of the Weizmann Institute of
Science in Israel
who was not involved in the work.
(10) The company's scientists also report that when they then injected preformed AS fibrils into the brains of mice, BIIB054 slowed the self - templating spread of AS pathology across the brain (consistent with their
cell - culture study), and held much of the ensuing motor dysfunction at bay (9,10)(reducing it «by more than 50 percent» according to a
science journalist
who was present when they presented results at AD / PD 2017 (11)-RRB-.
Determining how ES
cell genes are modified by these epigenetic markers may explain these
cells» unique characteristics, said the scientists,
who are based at the Genome Institute of Singapore (GIS) and the Bioprocessing Technology Institute (BTI), both under the Agency for
Science, Technology and Research (A * STAR), as well as at the National University of Singapore (NUS).