Grant Title: 01787: Clinical advancement of RNA - transfected CD40 - B
cell vaccine technology for cancer therapy
Not exact matches
Today his company is developing a new cancer
vaccine technology that teaches immune
cells how to recognize and remove tumor
cells.
Moderna is a clinical stage pioneer of messenger RNA (mRNA) therapeutics and
vaccines, an entirely new drug
technology that directs the body's
cells to produce intracellular or secreted proteins.
Currently, most influenza
vaccines in the United States are produced using chicken eggs, while a few are made in
cell culture or by using recombinant DNA
technologies.
«It's a powerful
vaccine technology that efficiently delivers
vaccine components to the right
cells in the right tissues.
The
technology also improves
cell culture systems used to produce therapeutic proteins,
vaccines, and gene therapy vectors.
Cancer
Vaccine Collaborative researchers Danila Valmori, Maha Ayyoub, Immanuel Luescher, and colleagues develop the first tetramer
technology to monitor CD4 T
cell responses to cancer vaccination.
Massachusetts Institute of
Technology (MIT) researchers have discovered a new way to model malaria using stem
cells in a petri dish, which will allow them to test potential antimalarial drugs and
vaccines.
Scientific programs include: human genomic sequencing and analysis, synthetic genomics and exploration of new
vaccines using this
technology, and environmental and single
cell genomics to explore the vast unseen world of microbes living in the human body, the ocean, soil and air.
Important reports from the Weiner lab include the first DNA
vaccine studied for HIV as well as for cancer immune therapy of cutaneous T
cell lymphoma, the early development of DNA encoded genetic adjuvants, including IL - 12, advances in gene optimization, and advances in electroporation
technologies resulting in improved gene delivery.
VXGN has other potentially valuable assets, including a «a state - of - the - art biopharmaceutical manufacturing facility with a 1,000 - liter bioreactor that can be used to make
cell culture or microbial biologic products» and rights to specified percentages of future net sales relating to its anthrax
vaccine product candidate and related
technology.
VXGN has other potentially valuable assets, including a «state - of - the - art biopharmaceutical manufacturing facility with a 1,000 - liter bioreactor that can be used to make
cell culture or microbial biologic products» and rights to specified percentages of future net sales relating to its anthrax
vaccine product candidate and related
technology.
Flublok's novel manufacturing
technology allows for production of large quantities of the influenza virus protein, hemagglutinin (HA)-- the active ingredient in all inactivated influenza
vaccines that is essential for entry of the virus into
cells in the body.