Sentences with phrase «cell culture studies also»

Cell culture studies also show that inflammatory cytokines increase both sebum and keratin production [1,8].

Not exact matches

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

The new research, which studied the immortalization process using genome - engineered cells in culture and also tracked skin cells as they progressed from a mole into a malignant melanoma, suggests that telomerase plays a more complex role in cancer.

«This pilot study showed that the culture system not only allowed for efficient propagation of sperm stem cells, but also eliminated ALL cells,» said Sadri - Ardekani.

The research highlights the importance of studying the effects of drugs not only on the tumor cells in a culture plate, but also on the interaction of the tumor cells with their own microenvironment.

But while researchers have previously been able to infect cultures of human hepatocytes with HBV, the cells» limited lifespan has made it difficult to study the virus, says Bhatia, who is also a Howard Hughes Medical Institute investigator and a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

Studies by Bausch and others have also detected live Ebola virus in sexual fluids that can successfully grow in cell culture, suggesting it could also lead to infections in other individuals.

«Our stem cells also survive outside of mice, in a culture, so we can also manipulate them in a laboratory,» said Abad, adding that: «The next step is studying if these new stem cells are capable of efficiently generating different tissues such as that of the pancreas, liver or kidney.»

However, chondrogenesis assays in chick micromass cultures showed that enhanced signaling by the mutant R206H ACVR1 can be partially inhibited by the BMP antagonist Noggin, suggesting that in addition to BMP - independent activity by the R206H ACVR1 receptor, this mutant receptor is also responsive to BMP, consistent with previous BMP signaling pathway studies that used cells derived from FOP patients (48 — 50).

The cell density of cartilage is also very low, therefore, cell cultures offer an easier approach to study cellular responses of chondrocytic cells, e.g., to mechanical stimuli.

In addition to Doñana Biological Station (EBD - CSIC), also taking part in the project were the National Center for Genomic Analysis (CNAG - CRG); the Centre for Genomic Regulation (CRG); the Spanish National Cancer Research Center (CNIO); the Evolutionary Genomics Group of the Hospital del Mar Medical Research Institute (IMIM); the Institute of Evolutionary Biology (IBE, CSIC - UPF); the University Institute of Oncology of Asturias (IUOPA); the Institut de Biotecnologia i de Biomedicina and the Unit of Cell Culture of the Autonomous University of Barcelona (UAB); the Biological Research Center (CIB - CSIC) and the Catalan Institution for Research and Advanced Studies (ICREA).

(10) The company's scientists also report that when they then injected preformed AS fibrils into the brains of mice, BIIB054 slowed the self - templating spread of AS pathology across the brain (consistent with their cell - culture study), and held much of the ensuing motor dysfunction at bay (9,10)(reducing it «by more than 50 percent» according to a science journalist who was present when they presented results at AD / PD 2017 (11)-RRB-.

Results from this Shaffer Grant study also show that targeting antioxidants such as XJB -5-131 to the TM significantly attenuates expression and release of TGF - β2 from cultured human TM cells.

Resveratrol also decreases phase III protein synthesis and a study showed that in a cell culture this prevented acute myeloid leukemia cells from becoming resistant to the chemotherapy drug doxorubicin (24).

Our study also suggests that cellular responses to future ocean conditions are not likely to be straightforward, as shifts in calcification may have less to do with calcification - related genes and more to do with intracellular regulatory processes in cells grown under continuous culture for many hundreds of generations.