Sentences with phrase «cell therapy enables»

Not exact matches

Jefferies analysts called the potential acquisition «smart,» because «the buyout would enable Celgene to integrate Juno's entire cell therapy platform and bring it all in house.»

The triggering of PARP enables cancer cells to withstand anti-hormone therapy treatment, causing cells to cultivate and develop into a more aggressive form.

Researchers at the University of Louisville have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies for diseases such as muscular dystrophy.

Enabling scientists to grow the stem cells artificially from pluripotent stem cells could also lead to the development of personalized blood therapies, researchers say.

The gold - iron oxide core - shell nanorods may be useful in cancer therapy, with MRI imaging enabled by the iron oxide shell, and local heating created by the photothermal effect on the gold nanorod core killing cancer cells.

Denmeade says the combination of drugs that block testosterone production and receptors, called androgen deprivation therapy, may make prostate cancer more aggressive over time by enabling prostate cancer cells to subvert attempts to block testosterone receptors.

Its high reactivity has enabled its use in photodynamic therapy, in which light is used in combination with a photosensitizing drug to generate large amounts of singlet oxygen to kill cancer cells or various pathogens.

Likewise, when a targeted therapy blocks a pathway that enables tumors to grow, the cells usually manage to get around that obstacle.

A better understanding of the process that enables these cancer cells to remodel bone may aid in the search for new therapies.

Other blood disorders that have shown significant benefit from targeted gene therapy in small trials include hemophilia (specifically, factor IX deficiency), severe beta - thalassemia (deficiency for the adult beta - globin gene) and leukemia, where the patient's immune cells were treated to enable them to recognize cancer cells and destroy them.

Chi said the new understanding of autophagy's role in regulatory T cells could enable a two-fold approach to immune therapy for cancers.

This pathway enables regenerative cell therapies to access the FDA's existing expedited programs to help foster the development and approval of these novel products.

Success is totally dependent on resolving a number of factors unique to cells as therapies, including: manufacturing, enabling technologies, regulation, reimbursement and essential infrastructure.

This should also enable commercialization of medical devices, reagents, and other products required for cell therapies through the development and dissemination of innovative methods and procedures for regenerative medicine based products.

With a team of over 200 researchers, Sanford Research is comprised of eight groups that bridge bench, translational and clinical research including: Cancer Biology and Immunotherapies, Pediatrics and Rare Diseases, Diabetes, Cellular Therapies and Stem Cell Biology, Enabling Technology, Environmental Influences on Health and Disease, Genetics and Genomics, and Population Health.

The program includes six focused research areas 1) cardiovascular regeneration, 2) urology, 3) gastrointestinal / endocrinology (liver, pancreas, ovary), 4) musculoskeletal, 5) stem cells / cell therapy and 6) biomaterials / enabling technologies.

Clinical research has shown that stem cell therapy can enable back pain sufferers to avoid spine surgery.

To enable scaling long term, we have entered into an agreement with Cell Therapy Catapult Services, a research organization specializing in the development of technologies which speed the growth of the cell and gene therapy indusCell Therapy Catapult Services, a research organization specializing in the development of technologies which speed the growth of the cell and gene therapy inTherapy Catapult Services, a research organization specializing in the development of technologies which speed the growth of the cell and gene therapy induscell and gene therapy intherapy industry.

Studying the molecular mechanisms that enable the metastatic cells to remain in dormancy for so long and then wake up and generate these macrometastases will allow us to develop therapies to prevent relapse, or, if metastasis occurs, to make it chronic or even stop it from spreading.

It was created to support development and commercialization of regenerative medicines and associated enabling technologies, with a specific focus on cell and gene therapy.

These findings will enable increasing numbers of researchers across the world to use these stem - cell like cells to study disease and explore potential regenerative therapies.

It will be a place where therapy manufacturers and developers can solve problems together with experts in the industry and come up with crucial manufacturing technologies and workflow solutions that could enable industrial - scale cell therapy manufacturing.

Harnessing the powerful healing properties of adult stem cells found in your own fat tissue, Okyanos Cell Therapy offers new hope for this neurodegenerative condition by enabling brain and nerve cell repair for the chance at an improved quality of lCell Therapy offers new hope for this neurodegenerative condition by enabling brain and nerve cell repair for the chance at an improved quality of lcell repair for the chance at an improved quality of life.

The results of her project will help scientists develop novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other cancer stem cells, with the goal of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant cancer cells.

«Completing the Human Cell Atlas is a mammoth task that needs the participation of many international collaborations and the combined knowledge - base will be an immeasurably valuable tool to model the plethora of dynamic components that enable life and to create a resource that can be used to explore new ideas for therapies and diagnostics in the near future».

Gentner B, Visigalli I, Hiramatsu H, Lechman E, Ungari S, Giustacchini A, Schira G, Amendola M, Quattrini A, Martino S, Orlacchio A, Dick JE, Biffi A, Naldini L. Identification of hematopoietic stem cell - specific miRNAs enables gene therapy of globoid cell leukodystrophy.

Developing Cell Therapies: Enabling Cost Prediction By Value Systems Modeling to Manage Developmental Risk.

In a statement, Paul Grayson, president and CEO of Fate Therapeutics, said: «Dr. Jaenisch's prescient vision in 2003 for creating human iPS [cells], and how reprogrammed cells could be used to revolutionize drug discovery and enable cell - based therapies, is truly unparalleled.»

He's also the scientist who developed the stem cell therapy that enabled crippled rats to walk.

Another recent grant, awarded to Sandra Gollnick, PhD, Director of the Photodynamic Therapy Center, Member of the Department of Cell Stress Biology and Distinguished Professor in the Department of Immunology, will enable the creation of an international registry compiling information about patients» responses to photodynamic therapy (PDT), an approach developed at Roswell Park that is now used in the treatment of many lung, esophageal, head and neck, pancreatic, and mesothelioma Therapy Center, Member of the Department of Cell Stress Biology and Distinguished Professor in the Department of Immunology, will enable the creation of an international registry compiling information about patients» responses to photodynamic therapy (PDT), an approach developed at Roswell Park that is now used in the treatment of many lung, esophageal, head and neck, pancreatic, and mesothelioma therapy (PDT), an approach developed at Roswell Park that is now used in the treatment of many lung, esophageal, head and neck, pancreatic, and mesothelioma tumors.

The 2012 study showed that many of the same mutations enabling colorectal cancer cells to metastasize and resist conventional therapies are the very facets that make them sensitive to treatment with grape seed extract.