Not exact matches
ReInnervate, a start - up in Durham, England, is developing a tiny, three - dimensional plastic scaffolding on which human
cells can be grown into artificial
tissue, and perhaps eventually into replacements for
organs.
He earned degrees in
cell biology and
tissue engineering and eventually got a job in a lab run by Vladimir Mironov, who was investigating the use of bioprinting — 3 - D printing using living
cells — to generate replacement
organs.
A research group at Cincinnati Children's Hospital Medical Center used human pluripotent stem
cells (hPSCs) to grow human stomach
tissue (paywall)-- and, notably, the part of the
organ that produces digestive enzymes.
The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with
cells, others which answer to Aristotle's levels of
tissues and
organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.
Then there are societies of
cells in
organs and
tissues; some of these societies may be dispersed widely through the body, as in the case of blood
cells.
What we eat becomes our
cells, our blood,
tissues,
organs, skin... We create health with what we put in our bodies.
Coconut oil provides many benefits including the ability to regulate blood sugar and hormone levels, boost thyroid function, fuel the human body's metabolic demands and provide healing support to
cells,
tissue and
organs.
Intermittent fasting allows the body to shed off inferior
cells and dump toxins out of the fat
cells and deep within
organ tissues.
Your body uses iron to produce red blood
cells which then provide oxygen to your
tissues and
organs (and your baby!).
Beef is a good source of protein needed for the growth of
tissues,
cells, and
organs in the body of the embryo and relevant for the healing and reparation of damaged
tissues during childbirth.
It's a rich source of stem
cells, particularly those that can grow into
tissues,
organs, and blood vessels.
As well as allowing the use of stem
cells grown from established
cell lines, the technology could enable the creation of improved human
tissue models for drug testing and potentially even purpose - built replacement
organs.
The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the
cell; physiology examines the physical and chemical functions of the
tissues and
organ systems of an organism; and ecology examines how various organisms interrelate.
For unknown reasons our immune system attacks healthy
cells,
tissues and
organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.
Stem
cells in babies» urine seem to help regenerate kidney
tissue, protecting it from toxic drugs and could pep up
organs for transplantation
These «
organs on a chip,» as they are called, are typically glass slides coated with human
cells that have been configured to mimic a particular
tissue or interface between
tissues.
The results were spectacular: The luminous protein made it possible to glimpse the inner workings of
cells,
tissues, and
organs in unprecedented detail.
In an amazing feat of
tissue engineering, Anthony Atala and his research team at the Children's Hospital in Boston are creating new
organs in the laboratory using patients» own
cells and by employing the same technology used to clone Dolly the sheep.
The secret to repairing our
tissues and growing new
organs is getting all touchy - feely with
cells
BUILDING artificial
tissue could become child's play, if Lego - like blocks made of human
cells can be assembled into working
organs.
Experiments on Earth using microgravity have shown that stem
cells — the master
cells that produce all
organ and
tissue cell types — will grow faster, compared to conventionally grown
cells.
Abba Zubair, M.D., Ph.D, believes that
cells grown in the International Space Station (ISS) could help patients recover from a stroke, and that it may even be possible to generate human
tissues and
organs in space.
«Knowing how
cells respond to mechanical cues in the living embryo and how they physically sculpt
tissues and
organs in the 3D space will transform the way we think about developmental processes,» said Otger Campàs, a professor in the Department of Mechanical Engineering at UCSB and senior author on the paper that reports this novel technique in Nature Methods.
These techniques include: human
tissue created by reprogramming
cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human
tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual
organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.
Whether building
organs or maintaining healthy adult
tissues,
cells use biochemical and mechanical cues from their environment to make important decisions, such as becoming a neuron, a skin
cell or a heart
cell.
As prostate cancer progresses, tumor
cells may infiltrate this periprostatic adipose
tissue: this is a key step in the progression of this cancer, as it signals locally advanced disease (where the cancer can progress to nearby
organs).
The
cells used to build the
organs could be cultured from stem
cells taken from fat or bone - marrow
tissue, he says: «We could engineer a blood vessel from your own
cells.»
As it can take weeks to grow human
cells into intact differentiated and functional
tissues within
Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter
tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of
cells cultured within these microfluidic devices over extended times.
Epithelial
cells form
tissue layers that cover our skin and the inner surfaces of most of our internal
organs, while endothelial
cells line the adjacent blood - transporting vessels and capillaries that support their functions.
Another challenge is producing stem -
cell - derived
tissues or
organs that don't develop teratomas — tumors that contain a variety of
tissues found in different
organs — when transplanted.
The cancer
cell is then able to penetrate the
tissue and set up a colonies at new
organ sites,» Halberg explains.
Scientists have focused for decades on the role of biochemical cues in embryonic development, Campàs said, because no techniques existed to measure the mechanical cues that
cells are exposed to during the formation of
tissues and
organs.
The scientists» findings have wide implications in the effort to understand how
organs are sculpted into their shapes and how
cells respond to their native mechanical environment both in healthy
tissues and during disease.
Four weeks after the team switched on the enzyme, they found that
tissue had regenerated in several
organs, new brain
cells were developing and the mice were living longer.
To get into the blood vessels, the
cell needs to penetrate
tissue, both when it leaves the tumour and when it is attaching to a new
organ.
The scientists have shown that, in all cancers, a sort of «identity crisis» is observed in cancerous
cells: in the
organs or
tissues in which a tumor develops, genes specific to other
tissues or to other stages of the development of the organism express themselves in an aberrant manner.
It is more profound in cancers that arise in
tissues with a high turnover rate, such as the skin and the epithelium, the thin layer of
cells that line many
organs.
For instance, medical researchers might succeed in creating complex
tissues and
organs derived from patients» own stem
cells.
In humans, the goal of SCNT is «nonreproductive cloning» — making embryos, then removing stem
cells from the embryo and cultivating them to grow into
tissues that could cure diseases, replace
organs and heal injuries.
Most animals, including humans, have two copies of their genome — the full set of instructions needed to make every
cell,
tissue, and
organ in the body.
Badylak's debut paper on ECM went to press right around the time scientists first coined the term «
tissue engineering» to describe what was then considered a small but burgeoning field — the far - out - there efforts to coax
cells into
tissue to restore, maintain, or improve
tissue function or whole
organs.
Change the size from 10 nanometers to 100 nanometers, and the drugs can end up in the wrong
cells or
organs and thereby damage healthy
tissues.
Hwang claimed to have perfected somatic
cell nuclear transplant, a procedure in which genetic material is removed from a donated egg and replaced with DNA from the patient to create cloned
cells that could regenerate diseased
tissues or
organs.
Over the course of three years, Horvath and his team analyzed nearly 8,000
tissue samples from these datasets, which included blood, saliva and
cells from
organs like the brain and the colon.
Tumours spread with the help of enzymes called matrix metalloproteinases (MMPs), which destroy the connective
tissue between
cells and
organs, allowing tumour
cells to break out of the original site and enter new ones.
Interdisciplinary research at the University of Pennsylvania is showing how
cells interact over long distances within fibrous
tissue, like that associated with many diseases of the liver, lungs and other
organs.
Lupus, or systemic lupus erythematosus, is a progressive, degenerative disease in which the immune system turns against itself, attacking a person's healthy
tissue,
cells and
organs.
Understanding exactly how stem
cells form into specific
organs and
tissues is the holy grail of regenerative medicine.
Therefore, these «self - reactive» T
cells survive destruction within an
organ called the thymus, the central immune
organ in which T -
cells mature, and attack healthy
cells and
tissues, including melanocytes.
Hilde Mangold (1898 - 1924) Under the guidance of Hans Spemann, she carried out the experiments that led to the discovery of the organizer effect, which directs the development of embryonic
cells into
tissues and
organs.