Cells in the body undergo stress all the time.
Cancer begins when one
cell in the body undergoes a genetic change that endows that cell and its clonal descendants a growth advantage vis - a-vis other cells.
Not exact matches
«B -
cells actually
undergo evolution
in real time
in your
body,» says Shlomchik.
Previous work
in Weinberg's lab had shown that after a tumor forms
in one part of the
body, some of the cancer
cells undergo EMT, Mani explains.
During their maturation process, T
cells in the thymus
undergo various tests requiring T
cell's antigen receptor to bind the
body's own molecules.
Future studies should explore whether stem
cells elsewhere
in the
body undergo a similar premature maturation, he says.
A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had
undergone a change
in character — from aggressive to static, and no longer shedding
cells that can colonize distant organs of the
body.
They homed
in on the function of the endoplasmic reticulum (ER)-- a «mini-organ» inside
cells where proteins and lipids are processed and packaged and
undergo quality control before they reach their destinations
in the
body.
This is contradictory to the common concept that cancer
cells undergo a series of mutations
in the course of tumor growth to acquire the ability to leave the primary site of the tumor and start migrating to other parts of the
body.