Cells use biological pathways to send and receive chemical cues in reaction to injury, infection or stress.
Not exact matches
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and
cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human
biological decline.
Using the idea of the inkjet printer, in which small nozzles shoot ink at the required area, the idea of inkjet - printed
biological cells was considered.
Improved understanding of the biology of cancer
cells has led to the development of
biological agents that mimic some of the natural signals that the body
uses to regulate growth.
The fields within biology are further divided based on the scale at which organisms are studied and the methods
used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of
biological molecules; cellular biology examines the basic building block of all life, the
cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.
They're also
used as
biological probes to image cancer and to study processes inside
cells,» Pentelute says.
The team's technique
uses a metal - organic - framework membrane that mimics the filtering function, or «ion selectivity,» of
biological cell membranes.
Chien Ho, professor of
biological sciences at Carnegie Mellon University, and his colleagues have developed a novel way to improve delivery of chemotherapy nanodrugs by
using Intralipid ®, an FDA - approved nutrition source to temporarily blunt the reticuloendothelial system — a network of
cells and tissues found throughout the body, including in the blood, lymph nodes, spleen and liver, that play an important role in the immune system.
Earlier, for his Ph.D., he
used his physics training to study
biological interactions at the molecular resolution — but for his postdoc he changed approaches dramatically, turning to
cell biology and applying his skills to the development of high - resolution functional imaging of DNA transcription in living
cells.
By monitoring stem
cell differentiation on gels that mimic the stiffness and nanofibrous structure of
biological tissue, researchers have identified the specific molecules that stem
cells use when selecting bone and cartilage fates.
«So
using this method we can look at interactions between four
biological components inside a
cell in three - dimension and at very high resolution of about 10 nanometers,» Xu said.
Taking inspiration from the
biological building methods
used in
cells and the ECM, the Bioinspired Soft Matter Unit, led by Prof. Zhang, has designed and synthesized a nanoscale toolkit of molecules that can interact together to assemble complex molecular structures.
While the man - made world is built
using either tension (for example, suspension bridges) or compression (brick walls), the
biological architecture of our
cells uses a combination of both called tensegrity.
«The surfaces of breast implants in
use today have relatively large features on their surface, which have no discernible correlation with
biological features required for
cells to interact with.
Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem
Cell Research in the Department of
Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely
used model for human kidneys.
The journal's home page explains that translational medicine «builds on basic research advances — studies of
biological processes
using cell cultures, for example, or animal models — and
uses them to develop new therapies or medical procedures.»
BORROWING a trick from the office photocopier may make it possible for a nanoscale printer to precisely manipulate
biological cells for
use in artificial tissue.
Researchers in the Departments of Biomedicine and Nephrology at the University Hospital and the University of Basel have discovered that the immune system
uses a molecular
biological clock to target intolerant T
cells during their maturation process.
The large rotelle - shaped molecules also can «catch» other molecules and thus would make effective
biological sensors; they also have potential
use in solar
cells and switches, he adds.
Researchers have long
used a different monkey species to research stem
cell transplants, but that species»
biological characteristics means it can't be reliably
used to find good donor matches to mimic human stem transplants.
A UCSF - led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before
using a process that turns human
cells into a
biological equivalent of LEGO bricks.
In this study, the researchers
used molecular,
cell biological, in vivo genetic and bioinformatics approaches to identify the EGFR ligand amphiregulin as a physiological substrate, and demonstrate a role for iRhoms in amphiregulin - EGFR - dependent wound healing.
This would have multiple goals of killing cancer
cells, creating a hostile
biological environment for their growth, reducing toxicity from the drug regimen and avoiding the development of resistance to the cancer drugs being
used.
In the final step in bacterial
cell division, constriction of the so - called Z - ring, an annular structure that forms on the plasma membrane near the midpoint of the
cell, gives rise to the two daughter
cells: A research team led by Erwin Frey, who holds the Chair of Statistical and
Biological Physics at LMU, has now used mathematical modelling to understand the mechanism that drives formation of the Z - ring, and in so doing have uncovered a novel class of pattern - forming mechanism in biologica
Biological Physics at LMU, has now
used mathematical modelling to understand the mechanism that drives formation of the Z - ring, and in so doing have uncovered a novel class of pattern - forming mechanism in
biologicalbiological systems.
A synchrotron is an important tool for many fields, as it creates intense beams of light that are
used to probe
biological cells or materials.
The Münster immunologists found a test - tube alternative for this, too: they
used the molecular
biological method of genome editing to systematically «cut out» the gene segment relevant for VLA4 and produce the appropriate «deficient» immune
cells.
Professor Alvaro Mata, from Queen Mary's School of Engineering and Materials Science, said: «The technique opens the possibility to design and create
biological scenarios like complex and specific
cell environments, which can be
used in different fields such as tissue engineering by creating constructs that resemble tissues or in vitro models that can be
used to test drugs in a more efficient manner.»
The new technique could also be
used to create nanoscale «inkjet printers» for printing electronics or
biological cells, or to create antennas or photonic components.
The research group has found that this technology allows scientists to inactivate critical
biological phenomena, including
cell migration and
cell division, by
using only lights, and without the assistance of chemical drug treatments or genetic modification.
«New printing technique
uses cells and molecules to recreate
biological structures.»
It is surprising to find that a single gene (ESRP), through its ancestral
biological role (
cell adherence and motility) has been
used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips, lungs or inner ears of humans,» states professor Jordi Garcia - Fernàndez, of the University of Barcelona's Department of Genetics, Microbiology and Statistics and the IBUB.
Researchers from Queen Mary University of London have developed a printing technique
using cells and molecules normally found in natural tissues to create constructs that resemble
biological structures.
LIG can be written into target materials in patterns and
used as a supercapacitor, an electrocatalyst for fuel
cells, radio - frequency identification (RFID) antennas and
biological sensors, among other potential applications.
But locating the
cells that contain the 50 - nanometer particles has been like looking for a needle in a haystack, in part because the tissue - dissolving methods
used to identify magnetite turn
biological samples to mush.
«This is another great example of how
using a synthetic «bottom - up» engineering approach and leveraging the power of
biological design — this time at the scale of individual molecules interacting on
cell membranes — can lead to breakthrough technologies for medicine that overcome limitations that hold back more conventional approaches,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children's Hospital and Professor of Bioengineering at Harvard's John A. Paulson School of Engineering and Applied Sciences.
Many of the adhesive products
used today are toxic to
cells, inflexible when they dry, and do not bind strongly to
biological tissue.
Roein - Peikar also noted that their experiments are mainly based on Chinese Ovary Hamster
cells, a
cell line derived from the ovary of the Chinese hamster, often
used in
biological and medical research.
The authors illustrate the power of their approach
using 20 distinct
biological systems ranging from single - molecule binding kinetics to
cell migration and division, immunology, and embryonic development.
Researchers
use it to examine
biological materials (such as microorganisms and
cells), a variety of large molecules, medical biopsy samples, metals and crystalline structures, and the characteristics of various surfaces.
They did wave around a vial filled with E. coli when announcing that the chemistry prize went to Osamu Shimomura, Martin Chalfie, and Roger TsienThey discovered and developed green fluorescent protein which is now
used to light up
cells making it possible to observe
biological processes.
Instead we can
use the epigenetic clock to monitor their
cells» aging rate and to evaluate which therapies slow the
biological aging process,» explained Horvath.
«Likely
biological link found between Zika virus, microcephaly: Discovery with lab - grown stem
cells could be
used to identify potential therapies.»
A team led by Dr. Thorsten Eierhoff and Junior Professor Dr. Winfried Römer from the Institute of Biology II, members of the Cluster of Excellence BIOSS Centre for
Biological Signalling Studies of the University of Freiburg, has identified a novel mechanism of bacterial invasion: Pseudomonas aeruginosa
uses lipids in the
cell membrane to make its way into host
cells.
An alternative approach is to persuade the immune system to attack tumours,
using vaccines,
biological therapies such as alpha interferon or interleukin 2 and genetically altered white blood
cells.
Contact: 508-289-7139;
[email protected] WOODS HOLE, Mass. —
Using a simple «mirror trick» and not - so - simple computational analysis, scientists affiliated with the Marine
Biological Laboratory (MBL) have considerably improved the speed, efficiency, and resolution of a light - sheet microscope, with broad applications for enhanced imaging of live
cells and embryos.
«Cadmium isn't
used in
biological systems (with one rare exception) which means that
cells haven't evolved ways to deal with this metal when they encounter it,» says Dr McDevitt.
Martonvásár Development of new generic plant genotypes to satisfy the needs of the future, based on an internationally acknowledged plant gene pool, and
using up - to - date genetic, physiological,
cell and reproduction
biological, functional genomic, biotechnological, plant breeding and crop production methods.
Through the
use of immunological, molecular and
cell biological techniques, my laboratory is defining the phenotype and function of different monocyte subsets that infiltrate the central nervous system following traumatic injury.
Belmonte
uses very early - stage pig embryos, whose
biological signals are capable of turning human stem
cells into the «perfect human organs» he's after.
Alternatively, evolutionary approaches have been
used to identify functional regions as those that are likely to have a measurable
biological impact on
cell function if perturbed.