Trastuzumab directly inhibits the proliferation of HER2 - overexpressing breast cancer cells and induces immune - mediated killing of target cancer cells through antibody - dependent
cellular cytotoxicity [20].
A failure to repair DNA lesions can result in mutagenesis, large scale genome aberrations and
cellular cytotoxicity.
Rituximab is thought to function through activation of natural killer cells, resulting in
cellular cytotoxicity.
Antibody dependant
cellular cytotoxicity (ADCC)- When antibodies coat an HIV - infected cell identifying it as something abnormal that needs to be killed.
Not exact matches
They can be localized within or on
cellular plasma membranes and have low
cytotoxicity when interfaced with experimental brain systems.
Though this exploitation of biochemical and
cellular pathways, the Gelipo - TRAIL - Dox combo accumulated more than the controls in the affected tumor tissue and had a greater
cytotoxicity.
The bioconjugate and unmodified QD treatments (the control) were tested for
cellular uptake and
cytotoxicity in MCF7 (cancerous) and MCF - 10A (comparison) cell cultures.