Mar. 12, 2015 — The question of what's different about pragmatic research was aired in a well - attended panel discussion last week in Light Hall sponsored by the Vanderbilt Center for Health Services Research and the Mid-South
Clinical Data Research Network (CDRN).
Recruitment methods for survey research: Findings from the Mid-South
Clinical Data Research Network.
Not exact matches
«We had been offering our Depression Care service for a number of years, and we wanted to dig into our
data and measure our impact... look and see who our end users were,» says Barb Vader, Vice President,
Clinical Services at Morneau Shepell, and the study's
research lead.
Among them: «a lack of
data standards in treating cancer, lack of
data sharing in the
research and development enterprise, lack of patient input and participation in
clinical trials,» and more.
To get to this point, St Jude and a few other
research hospitals that are piloting similar schemes have had to develop a great deal of infrastructure, train their
clinical staff in how to respond to genetic
data, and secure the significant funding these schemes require.
Lastly, Dr. Zemojtel will discuss the
data obtained with the Avenio workflow from
clinical research subjects with ovarian cancer.
ONC taps Accenture to create patient - generated health
data framework: Accenture Federal Services announced a two - year consulting contract with the ONC to help the federal government create a framework for collecting and using patient generated health
data in both
research and
clinical care.
Apple has used its HealthKit and ResearchKit software and
data platforms to connect users» health information across third - party apps and into
clinical research projects.
She is the Director of the Optimal Birth BC program, funded by the Canadian Institutes of Health
Research, which develops syntheses of evidence for clinicians, decision - aids and information packages for childbearing families, and uses local
data to evaluate
clinical practice and direct change to reduce rates of cesarean section in BC hospitals and health authorities.
The purposes of this Committee Opinion are to review the current literature concerning the reported benefits and risks of immersion in water during labor and delivery and, based on these
data, to provide updated
clinical recommendations and support for well - designed
research regarding these practices.
With years of
clinical, personal and
research experience, Suzanne Colson uses
research data to interpret breastfeeding behaviors in their natural habitat... mother's body.
It's important to note that the
research is on the properties of the vernix, but as of now, there is no
clinical data to prove this connection.
Semi - annual journal featuring
research, theory, case studies,
clinical intervention
data.
«
Clinical data were gathered through a retrospective review of records by the
research team who were not involved in providing care.»
Goswami agreed with an audience member that
data scientists could learn from the field of medical ethics and the institutional review boards that oversee issues such as informed consent in
clinical research.
Improving
Data Collection for Patient Care and
Clinical Trials The pharmaceutical industry faces a compelling need to improve to improve its
research processes.
Clinical research also makes you collect
data for a long time without seeing the results — this is quite a shock if you always have done lab
research.
«They are developing the
clinical genomics necessary to foster and support the Precision Medicine Initiative of the National Institutes of Health, and generating the genomics
data that further drives human genome
research.»
In an effort to find out, Stephen P. Juraschek, M.D., Ph.D.,
research and
clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used
data from the DASH (Dietary Approaches to Stop Hypertension)
clinical trial, a widely popular and often - cited study whose results were first published in 1997.
The project will ease the burden of validating the source of
clinical research data and improve quality and efficiency by eliminating manual and redundant
data entry.
This project includes a trial at Duke University that tests the idea of capturing
clinical trial
data in a single source and sharing the
data using standard protocols, with direct implications for future
research procedures and health care quality.
Crowley and Canzater identify five critical actions that should be priorities for monitoring HCV: 1) expand and standardize reporting to the CDC, 2) utilize electronic medical records to collect
data on HCV cases and the cure cascade, 3) fund epidemiologic
research using
clinical data sets, 4) integrate improved monitoring of HCV with responses to the opioid epidemic, and 5) establish and monitor HCV elimination plans across major US health systems.
The programme will ensure discoveries from the lab rapidly reach patients, and that
data from
clinical trials feed back into
research of the disease.
«For several years the potential for the use of gene expression
data in
research and
clinical applications has been underappreciated due to the inconsistency of the
data coming from the various types of equipment.
Led by Dr Steven Marwaha, a
clinical academic Psychiatrist, the
research analysed
data from the Avon Longitudinal Study of Parents and Children and found that teenage cannabis use at least 2 - 3 times weekly is directly associated with suffering from symptoms of hypomania in later years.
Previous
research has largely focused on dietary components and which diet would be best to lower the risk of obesity and type 2 diabetes, but so far there is no clear evidence from epidemiological or
clinical trial
data that a specific diet is optimal for long - term weight - loss or lowering the risk of diabetes.
Besides working at IBM's Thomas J. Watson
Research Center in Yorktown Heights, New York, Meyer heads something called the DREAM challenges, contests that ask teams of computer scientists to solve outstanding biomedical problems, such as predicting the outcome of prostate cancer treatment based on
clinical variables or detecting breast cancer from mammogram
data.
If confirmed by
clinical research, the
data points to the possibility that early pharmaceutical intervention could make a significant difference in the development of the disease.
The
research, led by Knut Wittkowski, biostatistician in the Center for
Clinical and Translational Science at The Rockefeller University Hospital, is a twist on a traditional
data - mining technique known as a genome - wide association study.
Using simple statistics, without
data about published
research, Ioannidis argued that the results of large, randomized
clinical trials — the gold standard of human
research — were likely to be wrong 15 percent of the time and smaller, less rigorous studies are likely to fare even worse.
«Our
data show that social mechanisms substantially affect
clinical outcomes over long periods of time, and deserve
research attention comparable to biological and psychological factors.
Exomes and the
Clinical Research Conundrum: New Approaches to Enhancing the Value of Genomic
Data
Dr Chris Gale is supported by a Medical
Research Council (MRC) Clinician Scientist Fellowship to develop large, simple
clinical trials that use routinely recorded electronic health record
data held in the National Neonatal
Research Database (NNRD).
A
research group at the Sahlgrenska Academy has now analyzed
data from
clinical trials and can rebut this theory.
A small number of federal researchers deemed essential by their agencies would still report to work, such as those involved in caring for patients at NIH's
clinical research center, sustaining animal colonies in
research laboratories, or handling weather
data seen vital to public safety.
Researchers used
data from the United Kingdom
Clinical Practice
Research Datalink and identified 52,298 patients who received a levothyroxine prescription between 2001 and 2009.
In order to examine the «placebo breaking the blind» theory, a
research group at the Sahlgrenska Academy in Gothenburg, Sweden, has now analyzed
data from the
clinical trials that were once undertaken to establish the antidepressant efficacy of two of the most commonly used SSRIs, paroxetine and citalopram.
The
research team, led by Benjamin Abella, MD, MPhil,
clinical research director of the Center for Resuscitation Science, examined
data on 7,137 cardiac arrest cases across 47 counties in 2012 and 2013 from Pennsylvania's Cardiac Arrest Registry to Enhance Survival (CARES).
Melina R. Kibbe, M.D., of the University of North Carolina at Chapel Hill (formerly of Northwestern University, Chicago), and Editor, JAMA Surgery, and colleagues conducted a study to determine if sex bias exists in human surgical
clinical research, if
data are reported and analyzed using sex as an independent variable, and to identify specialties in which the greatest and least sex biases exist.
They have the opportunity to be exposed to a wide variety of
clinical and patient - oriented
research, from Phase I, II, and III trials to collection of samples and
clinical data used to identify genetic variation that leads to human disease.
Adequately controlling for sex as a variable with inclusion,
data reporting, and
data analysis is important because
data derived from
clinical research are the foundation for evidence - based medicine.
Other studies have attempted to determine how the
research activities of MSTP graduates differ from those of other groups of MD and MD / PhD recipients.7 - 10 Although the
data from these studies suggest that a large majority of MSTP graduates hold appointments in
clinical departments, and that most have
clinical responsibilities, MSTP graduates are less likely than other groups of physician - investigators to publish in journals containing high proportions of
clinical observations and
clinical studies.
The researchers used
data from 6,871 male and 801 female admissions to a state prison system to compare the DSM - 5 severity index for alcohol use disorder to the ICD - 10
clinical and
research formulations for harmful use and dependence.
India's established leadership in information technology and industry
data management will help deliver
clinical trial
research data at lower cost and makes it a preferred destination for outsourced
clinical trials.
Further
research incorporating patient outcomes and
data from actual
clinical interactions is warranted to clarify the effect of clinician implicit bias on the provision of health care and outcomes,» the study concludes.
Clinical trials are the gold standard of
research, but the body of scientific
data should be compelling before translating scientific findings to our at - risk, presumed healthy patients for disease prevention and patients with a good prognosis undergoing treatment.»
Researchers working with stem cells should follow the example of their colleagues in genetic sequencing and
clinical research, setting up global networks for sharing
data, materials, and intellectual property, according to a report released today in Washington, D.C..
Icahn School of Medicine at Mount Sinai, is where the CTSN's DCC is based which directs each of its
clinical trial's design, methodologies, ethical
research concerns, study
data, analysis and reporting.
Miller says the response in this study, published in the Journal of
Clinical Lipidology, may confirm other
research findings about polyunsaturated fats: «Recent
data suggest that PUFA (but not MUFA) activates signaling in the brain to reduce appetite, so this may be one reason for the bigger weight drop between the groups.»
The next step for the
research team will be to test the algorithm in different populations and increase the decision power of the system with continuous updates on lung function
data with a validated
clinical diagnosis.