This is the conclusion of Stefan Hagel, Andreas Stallmach, Maria Vehreschild, and co-authors and of the members of the German
Clinical Microbiome Study Group in their article in the current issue of the Deutsches Ärzteblatt International.
Not exact matches
Some small
studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut
microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale
clinical trials focusing on each of those conditions are needed.
«It also brings in the question of diet,» says Wargo, who is now working on new
clinical studies on the
microbiome with the Parker Institute for Cancer Immunotherapy.
His team hopes to build a predictive model of the human
microbiome as a tool to
study how medical conditions can change this massive biological system, to identify settings that promote beneficial
microbiomes, and to design
clinical interventions to treat currently hard - to - manage problems.
«With this
study, we sought to characterize preschool - age children's supragingival
microbiome composition according to
clinical statuses of health («caries - free»), «restored disease» and «non-restored» or «untreated» disease,» said Kimon Divaris.
It won't be more widely used until we have the technology to analyze a
microbiome precisely in a
clinical setting, and until that planned double - blind
study takes place.
Other investigators on this
study were Caitlin E. Millett, graduate student, psychiatry and neural and behavioral sciences; Dahlia Mukherjee, postdoctoral fellow, and Aubrey Reider, research assistant, in the Department of Psychiatry, and Shannon L. Kelleher, an associate professor of cellular and molecular physiology, pharmacology, and surgery; Adem Can, University of Maryland School of Medicine; Maureen Groer, University of South Florida, School of Nursing, and Innsbruck Medical University, Austria; Dietmar Fuchs, Innsbruck Medical University, Austria; and Teodor T. Postolache, University of Maryland School of Medicine, Rocky Mountain Mental Illness Research, Education and
Clinical Center (MIRECC), and The Military and Veteran
Microbiome Consortium for Research and Education, MVM — Core.
Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood
microbiome in patients with liver cirrhosis; A randomized
clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf
microbiomes in the wild strawberry plant
Longitudinal
study of the psoriasis - associated skin
microbiome during therapy with ustekinumab in a randomized Phase 3b
clinical trial — Michael Loesche — Journal of Investigative Dermatology
Until I can read good
clinical studies showing that these chemicals or additives cause no harm to the skin
microbiome, I will continue to assume there may be harm, and will avoid them.