Sentences with phrase «coa carboxylase»
When insulin and acetyl - coA are increased, insulin activates an enzyme called acetyl - coA carboxylase (ACC)[8].
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AMP - activated protein kinase (AMPK) plays a central role in controlling hepatic lipid metabolism through modulating the downstream acetyl CoA carboxylase (ACC) and carnitine palmitoyl transferase 1 (CPT - 1) pathway.
The effect of a 3 - month low - intensity endurance training program on fat oxidation and acetyl - CoA carboxylase - 2 expression
Phosphorylation of both acetyl CoA carboxylase and AMP - activated protein kinase was increased, thus explaining the increase in fatty acid oxidation.
This enzyme, formally acetyl - CoA carboxylase, is of interest to researchers developing therapies for metabolic diseases such as obesity and diabetes and for certain cancers in which ACC is upregulated.
Evidence of interallelic complementation at clinically relevant loci is limited to biochemical and cell - based studies of a handful of metabolic disorders with defects in enzymes including propinyl - CoA carboxylase [2], argininosuccinate lyase [3], galactose -1-phosphate uridylyltransferase [4], and methylmalonyl CoA mutase [5].
They further established that the protein produced by the BRCA 1 gene binds with a protein known to play an important role in the metabolism of fat in muscle cells known as Acetyl - CoA carboxylase or ACC.
In their detective work to uncover what causes fatty liver, the scientists studied mice that have a «genetic disruption» to a single amino acid in two proteins called acetyl - CoA carboxylase (ACC).