Sentences with phrase «coa dehydrogenase»

A week after her birth, I learned I would have a harder path ahead than I had expected: The doctors told me that my daughter was born with a rare genetic condition called medium chain acyl CoA dehydrogenase deficiency.

The study also looked at «citrate synthase (CS) and 3 - hydroxy - CoA dehydrogenase (HAD)» activity in the vastus lateralis muscle.

Abbreviations: LDLR = LDL receptor; APOB / A1 = apolipoprotein B - 100 / A1; PCSK9 = proprotein convertase subtilisin / kexin type 9; SREBP - 1 / 2 = sterol regulatory element - binding protein 1/2; LPL = lipoprotein lipase; FATP2 / 4/5 = fatty acid transporter protein 2 / 4/5; FASN = fatty acid synthase; SCD5 = stearoyl - CoA desaturase 5; ACADL = acyl - CoA dehydrogenase; L - FABP = liver fatty acid - binding protein; and CPT1A = carnitine O - palmitoyltransferase 1.

A spike at C - 8 indicates something called medium - chain acyl - CoA dehydrogenase deficiency, which mercifully can be shortened to the acronym MCADD.

Not exact matches

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

(3) The researchers noted that the muscles of mice fed the MCTs produced higher levels of key metabolic enzymes (3 - oxo acid CoA - transferase, citrate synthase and malate dehydrogenase) involved in the Krebs cycle (tricarboxylic acid cycle), the body's primary energy production mechanism.