Sentences with phrase «coagulation factors v»
February 01, 2008 Dr. Bin Zhang, PhD awarded prestigious Basil O'Connor Starter Scholar Research Award from March of Dimes The March of Dimes Foundation has awarded Bin Zhang, PhD, Assistant Staff, GMI, a Basil O'Connor Starter Scholar Award for his proposed work entitled,» Receptor - Mediated ER - to - Golgi Transport of Coagulation Factors V and VIII: Deficiencies in the Early Secretory Pathway as Pathogenic Mechanisms of Congenital Disorders.»
http://www.lerner.ccf.org/ Not exact matches
The researchers found that patients both experiencing a reactional episode and those with non-reactional leprosy had factors in their blood — including plasmatic fibrinogen, anti-cardiolipin antibodies, von Willebrand factor, and soluble tissue factor — promoting blood coagulation.
An international team of scientists have published a study in The Journal of Clinical Investigation, where they show that the disease is caused by a defective blood protein, the so - called coagulation factor XII.
The strategy of giving a higher proportion of plasma is based on the belief that maintaining the balance of coagulation factors carried in plasma would reduce the overall amount of bleeding, requiring lower amounts of red blood cells and improving survival.
The increased production of PAI - 1 and factor VII has been implicated in the development of coagulation and fibrinolytic abnormalities characteristic of obesity (28, 70).
Factor VIIIa is also inactivated by a protein in the coagulation cascade called activated protein C. Gale and his colleagues hope that activated protein C would still be able to degrade Factor VIIIa and that clotting would not get out of hand.
Inclusion Criteria: Subjects must have histologically or cytologically confirmed metastatic cutaneous or mucosal melanoma, Able to swallow and retain orally administered medication, Adequate hematological, renal, hepatic, and coagulation laboratory assessments Exclusion Criteria: Clinically significant bleeding within 4 weeks of screening, Current use of warfarin, factor Xa inhibitors, and direct thrombin inhibitors, Infection requiring anti-infective treatments within 1 week of study enrollment, Anti-tumor therapy, Major surgery within 28 days
The condition is a result of a deficiency or dysfunction in a coagulation factor known as Factor IX and it currently has nofactor known as Factor IX and it currently has noFactor IX and it currently has no cure.
When injured, hemophiliacs tend to have a slow clotting (coagulation) process because of the lack of necessary blood factors (proteins).
In collaboration with an international team, researchers at Karolinska Institutet in Sweden have developed an antibody, 3F7, which blocks a protein that is active in the coagulation system factor XII.
Coagulation genetic markers, such as Factor V Leiden and Prothrombin G20210A Mutation, determine whether a patient is at significantly higher risk for blood clotting.
Dogs affected with VWDI have less than half of the normal level of von Willebrand coagulation factor (vWf), which is an essential protein needed for normal blood clotting.