Sentences with phrase «conducted clinical phase»

-- Recruited and interviewed study participants — Arranged patient visits — Created source documents, maintained reports and met with monitors on routine site visits — Conducted clinical Phase II through IV trials for the Multispecialty site

Not exact matches

«The next steps in DPX - RSV will be expensive steps (large RSV infection avoidance studies, or perhaps even challenge studies, will need to be conducted in Phase 3), and so we agree with management's strategy to identify cash - contributing partners before investing its own capital in new DPX - RSV clinical initiatives,» he added.

Eli Lilly runs the large, multinational clinical trials — conducted in phases I, II and III — that the Food and Drug Administration requires before approving a new drug.

Already, Phase 1 clinical trials are being conducted with specific IDH1 / 2 mutations.

Researchers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial.

The drug was developed by Lawrence - based CritiTech, and the drug - testing and phase I clinical trial were conducted by KU Cancer Center researchers, led by Stephen Williamson, M.D., medical director of Cancer Clinicalclinical trial were conducted by KU Cancer Center researchers, led by Stephen Williamson, M.D., medical director of Cancer ClinicalClinical Trials.

Investigators now are considering conducting an early - phase clinical trial in which healthy participants would consume a low - asparagine diet.

The company has already garnered a fair amount of attention and is funded by the US National Institutes of Health (NIH) in Bethesda, Maryland, to conduct a phase II clinical trial in people with pain conditions such as neuralgia, fibromyalgia or migraines.

Northfield Laboratories, Inc., in Evanston, Ill., has been conducting clinical trials for its oxygen - carrying red blood cell substitute, PolyHeme, but in May said the product failed to meet the primary goals of mortality and safety in an important phase III study.

Independent of these preclinical studies, Clementia Pharmaceuticals is currently conducting phase 2 clinical trials in individuals with FOP, based on the 2011 preclinical results published by Pacifici and Iwamoto.

The phase 2 randomized clinical trial was conducted by the Eastern Cooperative Oncology Group, enrolling 245 patients with stage 3 or stage 4 metastatic melanoma who had been treated with other drugs.

A phase I trial conducted by investigators at the Colorado State University Veterinary School in 30 dogs with non-Hodgkin's lymphoma with HCQ and the standard chemotherapy doxorubicin (DOX) showed a 100 percent clinical benefit rate.

A phase I clinical trial conducted by investigators at the University of Texas San Antonio, showed that the combination of HCQ and the chemotherapy drug vorinostat in 27 patients with advanced solid tumors, including renal cell carcinoma and colon cancer, was clinically safe and inhibited autophagy.

The Phase 3 trial was funded by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), both part of the National Institutes of Health, and was conducted by the NIH - sponsored Clinical Islet Transplantation (CIT) Consortium.

It was conducted under a special protocol assessment with the US Food and Drug Administration, which considers an uncompleted Phase III trial's design, clinical endpoints, and statistical analyses acceptable for FDA approval.

In 2011, he established the Immunotherapeutics Clinical Core, a specialized phase 1 outpatient unit at MSK that is focused on the conduct of novel immunotherapy trials, with a specific emphasis on pharmacodynamic biomarker identification.

Next, the Sarepta team designed and conducted a Phase I clinical trial.

The study — conducted by the Clinical Investigator Collaborative, a multi-centre, Phase II clinical trials group supported by the Allergy, Genes and Environment Network (AllerGen)-- recruited 31 patients over five sites acrossClinical Investigator Collaborative, a multi-centre, Phase II clinical trials group supported by the Allergy, Genes and Environment Network (AllerGen)-- recruited 31 patients over five sites acrossclinical trials group supported by the Allergy, Genes and Environment Network (AllerGen)-- recruited 31 patients over five sites across Canada.

Since eye and vision research can be conducted noninvasively, advancement of trials from the preclinical to the clinical phase could be relatively fast.

Sanofi - aventis is conducting a phase III clinical trial in Thailand of its canarypox vector mixed with gp120.

The Phase III clinical trial, conducted by the Radiation Therapy Oncology Group (RTOG), randomized 637 patients at multiple centers, including the University of Maryland Greenebaum Cancer Center, into two groups.

Researchers at Massachusetts Eye and Ear / Harvard Medical School and the University of Crete have conducted a phase I / II clinical trial investigating the efficacy of statins (cholesterol - lowering medications) for the treatment of patients with the dry form of age - related macular degeneration (AMD)-- the leading cause of blindness in the developed world.

This prospective, single - arm, phase II clinical trial was conducted to evaluate the safety, feasibility, and efficacy of induction chemotherapy followed by SABR in 34 patients who had biopsy - proven PDA.

He is working closely with a team of physicians at the UNM Cancer Center to conduct these trials: M. Omar Chohan, MD, a neurosurgeon who specializes in surgery for tumors of the brain and spinal cord; Gregory Gan, MD, PhD, a radiation oncologist who is an expert in the radiation therapy of brain tumors; and Yanis Boumber, MD, PhD, a newly recruited medical oncologist to the UNM Cancer Center who is an expert in cancers of the lung, brain and spinal cord, and early phase clinical trials.

According to Tomas Cihlar, Ph.D., of Gilead Sciences, the company is currently conducting phase I clinical studies of the compound in healthy human volunteers to establish the safety and pharmacokinetic profile.

The second phase of clinical trials of the vaccine are underway in Brazil, conducted by Orygen Biotecnologia SA, and the Infectious Disease Research Institute, Seattle.

The next steps for this vaccine are to produce a clinical grade lot and conduct a phase 1 study of safety and immunogenicity in infants, Moore says.

The phase in the development of a new treatment where clinical trials are conducted using many patients, to determine whether the treatment is effective

ViaCyte is conducting a Phase 1/2 clinical trial of the Company's lead product candidate VC - 01 in patients with type 1 diabetes who have minimal to no insulin - producing beta cell function.

The HVTN is an international collaboration that conducts all phases of clinical trials, from evaluating experimental vaccines for safety and the ability to stimulate immune responses, to testing vaccine efficacy.

Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical trial next year of a third - party compound as part of a drug development program in asthma.

Later - phase clinical trials, which often take several years or more to conduct, often involve hundreds or thousands of patients.

Together these data will support future efforts to conduct Phase I clinical trials in humans and constitute significant progress on the pathway toward a vaccine for falciparum malaria.

To ensure engraftment without severe GVHD, O'Donnell has conducted Phase I / II clinical trials since 1999 in which a half - matched transplant is performed and then a high dose of chemotherapy is administered to the patient three days later.

The clinical trial is open labelled for the phase Ia arm conducted in Tübingen, Germany and double blinded for the phase Ib conducted at the Institut de Recherche Clinique du Bénin, Benin.

Since then, Aeras has helped develop 9 TB vaccine candidates and conducted over 35 Phase 1 - 2b clinical trials.

«As a national leader in designing, conducting and analyzing all phases of clinical trials, the University of Chicago is well positioned to play a leadership role in the new network,» said Michelle Le Beau, PhD, Arthur and Marian Edelstein Professor of Medicine and Director of the University of Chicago Medicine Comprehensive Cancer Center.

He conducts phase 1 and 2 clinical trials of novel targeted agents.

Its Clinical Trials Center conducts 13 - 15 clinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea laClinical Trials Center conducts 13 - 15 clinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea laclinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea laclinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea last year.

Ohio State is one of only 41 National Cancer Institute - designated Comprehensive Cancer Centers and one of only four centers funded by the NCI to conduct both phase I and phase II clinical trials on novel anticancer drugs.

Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.

Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.

Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical trial next year of a third - party compound as part of a drug development program in...

She is one of the few pediatric oncologists in the United States who is conducting Phase I clinical trials of promising treatments for the disease, and her team has established the only 131I - meta - iodobenzlyguanidine (MIBG) treatment program in Illinois.

ViaCyte is conducting a Phase 1/2 clinical trial, called STEP ONE, of the Company's lead product candidate VC - 01 in patients with T1D who have minimal to no insulin - producing beta cell function.

Phase II Trials clinical studies conducted to evaluate the effectiveness of the drug for a particular disease or signs or symptoms in patients with the disease or condition under study and to determine the common short - term side effects and risks.

Together, the three institutions will conduct early phase cancer clinical trials sponsored by the NCI, which has established the experimental trials network to help speed the drug development process.

These clinical trials are categorized into 3 phases, with each one being conducted to meet a specific requirement.

We have a particular speciality in advising on clinical trials and were instructed in the Northwick Park trial of the monoclonal antibody TGN1412 which led to a review of the conduct of all phase 1 clinical trials.