Sentences with phrase «controls gene expression»

Controls gene expression by turning on some genes while turning off the expression of other genes.

One of Kawakami's critical discoveries was that a protein that controls gene expression, called STAT5, drives up the number of mast cells in skin of some eczema sufferers.

«Taken together, the work represents a large step towards deciphering the code that controls gene expression, and provides an invaluable resource to scientists all over the world to further understand the function of the whole human genome», says Professor Taipale.

HNF - 4α controls gene expression in the liver and pancreas, switching genes on or off as needed.

The enzyme that demethylates histones has been identified, adding another component to the regulatory network that controls gene expression.

RNA is a fundamental molecule that codes for protein and controls gene expression, playing a part in regulating many cell responses and vital processes.

The drug, lapatinib, activates the suppressor called FOXO, in HER2 + breast cancer cells, but then FOXO becomes a turncoat molecule, working with an epigenetic regulator that controls gene expression.

NF - κB is a protein complex that controls gene expression.

Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

Cohesin controls gene expression and chromatin structure, as well as enabling chromosomes to separate correctly immediately prior to cell division.

In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNA.

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

DNA methylation is a mechanism cells use to control gene expression at the epigenetic level.

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

These play a key role in controlling gene expression and, thereby help regulate the cell's development, growth and function.

Now, using computer simulations, James Carothers and his colleagues at JBEI have sped up the RNA design phase, creating computer tools that will help researchers design molecules to precisely control gene expression in bacteria to optimize fuel production.

Furthermore, they found that the Sp7 transcription factor directly controlled gene expression of the Fgf ligands.

Kingsley's research has shown that these adaptive changes are often driven by changes in the regulatory regions that surround and control gene expression, rather than within the coding regions of the genes themselves.

DNA methylation, one mechanism of epigenetics, is a chemical tag on DNA that does not change the gene sequence but is involved in controlling gene expression.

DNA methylation is an epigenetic mechanism used by cells to control gene expression.

Light can be used as an accurate method to control gene expression, shows groundbreaking optogenetics study by University of Colorado, Duke University and University of Helsinki researchers.

It plays an important role in how cells sense their neighbors and, by controlling gene expression, determines which cells should develop into different types and how much they should grow - like a master controller.»

Given its critical role in controlling gene expression, SETDB1 must be precisely regulated to ensure that molecular processes run properly.

Molecular recognition is fundamental to transcriptional regulation, the primary mechanism by which cells control gene expression.

Believing that science and medicine are inextricably linked, he decided to do a PhD at the MRC Mill Hill laboratories and investigated the role of regulatory elements in controlling gene expression, graduating in 1996.

- catenin pathway activates certain lncRNAs to directly control gene expression in skin fibroblast cells.»

Different lengths correspond to different tensions of the spring and can control gene expression and disease traits.

The Center for RNA Research at the Institute for Basic Science has succeeded in revealing, for the first time, the mechanism of how miRNAs, which control gene expression, are regulated in the early embryonic stage.

Acetylation — the addition of a small clump of atoms called an acetyl group — may be the most important body process you have never heard of: It activates and deactivates proteins, thereby regulating access to our DNA and helping control gene expression.

Recent studies have expanded the search for genetic links from identifying genes toward epigenetics, the study of factors that control gene expression and looks at chemical modifications of DNA and the proteins associated with it.

Tapio, meanwhile, has adapted standard proteomics techniques so that they can be applied to some of the old tissues, and several groups are studying whether micro-RNAs — which help to control gene expression and are relatively stable — are present in the samples.

Previous groundbreaking work by Chuan He, PhD, professor of chemistry, biochemistry and molecular biology, and investigator at Howard Hughes Medical Institute at the University of Chicago, demonstrated that reversible methylation exists for messenger RNA to control gene expression.

More broadly, this landmark discovery has illuminated an unexplored avenue in scientists» understanding of how cells control gene expression, and will indubitably incite a fresh wave of innovation in this ever growing field.

The Cas9 system also can be used to control gene expression.

Synthetic RNA - protein modules integrated with native translation mechanisms to control gene expression in malaria parasites.

Dr. Saptarsi Haldar's research focuses on how cells in the cardiovascular system control gene expression and how these gene control mechanisms go awry during disease.

Nishikura studies the process of RNA editing and has made pioneering strides in the understanding of how our cells utilize RNA to control gene expression and protein synthesis and how the malfunction of this process can lead to disease.

Projects also address potential approaches to therapeutic genome editing, as well as epigenetic modifications to control gene expression.

In the second crucial step, they experimented with dozens of proteins known to control gene expression, especially during the formative process of embryo growth.

They demonstrated use of the LITEs to control gene expression in mouse neurons and in the brains of living mice both quickly and significantly.

Her research focuses on understanding how signaling pathways control gene expression, using T cells and other cells of the immune system as models.

The application of transgenesis and other genetic methods - in conjunction with total genome sequence and database information on gene expression patterns, morphological changes during development, and mutant phenotypes - should significantly enhance our ability to unravel the multilayered networks that control gene expression and differentiation.

Cre - lox recombination, discovered in the 1980s, is one of the most important ways to spatially and temporally control gene expression, especially in in vivo models, and new Cre - lox based technologies are still being developed today.

Chromatin loops, which allow contacts between regulatory elements controlling gene expression, displayed cell type - specific patterns (B cells vs. iPSCs)

The findings reported in Nature Genetics indicate that genome architecture has important informational value for controlling gene expression during cell reprogramming, and is thus required for the specialized functions of a cell.

Integrating this new information into computational models, my colleagues and I predicted that about 5 percent of HARs function as noncoding RNAs, while most are enhancers that control gene expression during embryonic development.9

While the role that DNA - binding proteins play in regulating gene expression at the transcriptional level is well studied, how RNA - binding proteins control gene expression at the post-transcriptional level is less clear.

If GFP could be co-opted to control gene expression, he could then selectively manipulate only GFP - labeled cells.

Because the scientists are controlling gene expression, they could use the lights to do other things besides make art.

Breeden anticipates using this method to identify coordinately regulated cell - cycle genes and ultimately elucidating the mechanisms that control their gene expression.