Not exact matches
The new research reveals how spatially intermixed
pyramidal neurons that were associated with single chandelier
cells in the mouse prelimbic
cortex segregated into two groups.
A recent generation of studies of postmortem brain tissue from people with schizophrenia, particularly from the laboratory of Professor David Lewis and his colleagues at the University of Pittsburgh, have shed light on schizophrenia - related abnormalities in the interplay of the main excitatory neurons,
pyramidal neurons, and a specific class of inhibitory nerve
cells, called chandelier
cells, in the prefrontal
cortex.
Fast - spiking interneurons are part of a general class of neurons whose primary role is regulating the activity of the principal
cells of the cerebral
cortex, known as
pyramidal cells.
For her dissertation, Prerana developed several bacTRAP transgenic mouse lines to characterize molecularly distinct cortical
pyramidal cell types, and focused on layer 2/3
pyramidal cell population in the prefrontal
cortex that moderate stress induced depression related behavior.