He is also developing a robust and comprehensive panel of 3 - D cell
culture models from patient - derived primary cells that can be used to characterize different disease phenotypes and investigate the chemo - response of cells to novel or known drugs.
Not exact matches
A business
model to match it is necessary, as is a
culture that facilitates success
from the top down.
«Businesses are diversifying
from traditional corporate
models, and spontaneity is becoming more valued,» says Estelle Tang, a
culture editor at Elle, where (no surprise) people tend to notice one another's clothes.
The others are organizational enablers: building the talent,
culture and operating
model to support digital success; developing capabilities to bring Big Data and analytics into decision making; and rebooting the IT backbone to free it
from its slow - moving legacy past.
This was supposed to help the new state distinguish itself
from the «three
cultures»
model institutionalized by the British.
«Based on the innovative
model from Start - Up Chile, Start - Up Chile launched with a mandate to attract foreign entrepreneurs to the local consumer market and foment domestic entrepreneurial
culture»
'» Asked to paint a picture of the company in 20 years, the executives mentioned such things as «on the cover of Business Week as a
model success story... the Fortune most admired top - ten list... the best science and business graduates want to work here... people on airplanes rave about one of our products to seatmates... 20 consecutive years of profitable growth... an entrepreneurial
culture that has spawned half a dozen new divisions
from within... management gurus use us as an example of excellent management and progressive thinking,» and so on.
In a
culture like our own, which exalts sex and disparages celibacy, it is little surprise that many fail when they attempt celibacy without much support
from the church, without clear
models, and without practical advice in facing the challenges they face.
In worship, art, architecture, literature, communal life, language, beliefs, moral values,
models of a virtuous life, views of the past, the persistence of an aristocratic
culture» in all of these aspects of life, a profound and far - reaching transformation of the society was underway, and the book would have benefited
from greater attention to at least some of them.
Effectively, there are 22,000 peasant - farmer organisations at the village level which, since 1967, try to propel economic development
from their
culture by opposing imported production
models.
Five years
from now, I might realize that there are ways to plug my convictions about disciple making and following Jesus into the mega-church
model, and that it offers the best way of reaching our
culture and helping people follow Jesus.
If I am governed only by the opinions and
models that I obtain
from my surrounding
culture then I am not really an individual.
Since Christ had liberated them
from male - dominated
culture and set them as
model leaders, the women became challenging figures more than men.
The ecological
model, when abstracted
from possible negative uses, provides us a way of thinking of e pluribus unum that avoids taking one extant
culture as normative or just leaving the many as many.
The growing difference within evangelicalism regarding contextualization is described helpfully by David Wells in his essay: «In the one understanding of contextualization, the revelatory trajectory moves only
from authoritative Word into contemporary
culture; in the other, the trajectory moves both
from text to context and
from context to text...» Increasingly, evangelicals are opting for the second of these
models - an «interactionist» approach, to use William Dymess» terminology.
Looking primarily to
models based on quantitative research methodologies to provide a clear direction for policy in regulating media and violence can also distract policy makers
from coming to grips with other difficult but more important value questions that impinge on the issue of media and violence, such as the purpose of broadcasting, issues of ownership and control of media, the international context of Australian media, the dominant economic nature of most of Australia's social communications, the distinctive ways in which the media reproduce and reconstruct myths and symbols of violence
from within the
culture, and how audiences use and respond to media myths and symbols.
Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again
from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business
model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant
culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent
from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business
model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke
model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...
«Climate science is a «data - heavy» discipline with many intellectually interesting questions that can benefit
from computational
modeling and prediction,» said Dovrolis, a professor in the School of Computer Science, «Cross-disciplinary collaborations are challenging at first — every discipline has its own language, preferred approach and research
culture — but they can be quite rewarding at the end.»
One postdoc presents data on her efforts to develop an organoid
model for small - cell lung cancer; another reports progress on
culturing hormone - secreting organoids
from human gut tissue.
The test procedure is performed on an in vitro skin
model built at Fraunhofer IGB
from human skin cells in special
culture dishes.
Critically, despite the detection of enhanced Zika infection in cell
culture models using antibodies
from macaques previously exposed to either yellow fever or dengue and then exposed to Zika, there were no signs of enhanced Zika infection seen in these macaques themselves.
When he genetically disabled or chemically modified the HSPGs in cell
cultures and in a mouse
model, clumps of tau could not enter cells, thus inhibiting the spread of misfolded tau
from cell to cell.
The study mostly makes use of
cultured cortical neurons
from rats, exploiting a wide array of molecular and imaging techniques to probe the mitochondrial function and well - being of neurons manipulated to
model Wolfram syndrome.
This work involves behavior, immunohistochemistry (of brain tissue
from mouse
models of Alzheimer's), cell
culture, and in vitro biochemistry.
For understanding the biology of gene - gene, gene - drug and gene - microenvironment interactions, a considerably broader range of in vitro and in vivo
model systems is required — we are generating 1,000 organoid
cultures from human cancers, characterising their genomes, functional dependencies and drug response, and we are expanding our in vivo
models to study the interface between cancer and the immune system and microenvironment.
Because neurodegenerative disorders like PD are largely diseases of aging,
modeling them in a
culture dish using neurons grown
from iPS cells has been thought to be exceedingly difficult, if not impossible.
«Our next steps are to extend these studies
from yeast and cell
culture into live animal
models.
Dr. Nociari uses animal
models, cell
culture, and clinical approaches to study
from different perspectives the impact that lipofuscin accumulation has in retinal disease.
These epithelial organoid
cultures are genetically and phenotypically extremely stable, allowing transplantation of the
cultured offspring of a single stem cell, as well as disease
modeling by growing organoids directly
from diseased patient tissues (45).
In 2013, his team developed an organ - on - a-chip microfluidic
culture device that
modeled the human kidney's proximal tubule, which is anatomically connected to the glomerulus and salvages ions
from urinary fluid.
We came across a compound that had been isolated
from a plant species and shown to have effects on blocking the growth of blood vessel cells, both in the
culture dish and also in animal
models.
I completed my Ph.D. in Microbiology in November 2016
from the University of Kansas after researching host cell - viral interactions of HSV - 1 in cell
culture models.
JORD draws inspiration
from Scandinavian
culture, and
models it after a modern lifestyle.
The website members usually belong to different communities, sometimes
from different countries, yet, most users will search their pair according to interests, geographical location,
culture and even relationship
model.
That family
model was completely not for me thats why I had made a decision about seeking for my future wife
from the country with different
culture and values.
The amount of direct new revenue
from PrivateCall is going to depend on the
culture, demographics, size, and business
model of each site.
I fell in love with Britain
from a very young age and just adore it's history, beauty and
culture, the English accents are just a bonus for me;) I'm a Trade Show
Model /...
They're all perfect little set pieces (and I suspect they're plastic
models) but there's culinary cuisine
from just about every
culture around the world.
Those goals include raising West Charlotte High School's graduation rate
from 54 percent in 2011 to 90 percent in 2016, and she saw that the Opportunity
Culture models could help by focusing on its eight feeder schools.
Districts are responding: As of spring 2014, four districts nationally are piloting Opportunity
Culture models, and one, Charlotte - Mecklenburg, is taking its pilot efforts to scale based on recruiting results and demand
from schools.
Craig Kemp (@mrkempnz) describes risk - taking as a «
culture of learning» and shares strategies
from classrooms around the globe that are helping to normalize struggle including, «support, encourage,
model (let them teach the class)», «encourage teachers to make mistakes so students see it is OK» and «provide plenty of choices to watch their inner genius interpret what to do.»
Excellent teachers
from Teach Plus and other experts contributed to the
models, alongside the initial Opportunity
Culture Advisory Team, which includes leaders in teaching, technology, and philanthropic organizations.
If schools are investing in staff training they should try and move away
from traditional CPD
models, creating a coffee shop
culture of collaboration.
To take
models from nature as instructive concerning how life works is not taught today, though it once formed the bedrock of understanding in all indigenous
cultures.
Create a Folktale Students write a folktale
modeled after tales
from Hispanic
cultures read and heard in class.
Living away
from home to study — Boarding schools: The Wunan Foundation boarding school
model seeks to foster students» connection to their home and
culture.
Probably the most thought - provoking portion of Professor Wax's essay is her discussion of how both
models — no - excuses and income mixing — «assume that, to succeed in school and in life, poor children need to be taught bourgeois, middle - class values — and socialized away
from their
culture of birth.»
In this
model, teachers consider moving
from merely topically introducing
culture in lessons to having students understand the perceptions of those
from different
cultures to finally identifying issues of inequality and discrimination and engaging in social action.
Johnson and Maxson McElroy: Everything else in our
culture has changed, such as the global business market, which has moved
from an assembly - line manufacturing concept to a more service - oriented
model.
Facing History's engagement with teachers and schools exists on a continuum,
from providing professional development, educational resources and support to individual teachers, to implementing a robust whole - school
model, which impacts the
culture of the entire school.