Not exact matches
Similar to primary keratinocytes, long - term —
cultured squamous cell carcinoma (30) and many other
epithelial cancer cells (30, 31) can also form different types of clones in
culture.
Interestingly, long - term —
cultured human
epithelial cancer cells in clonal
cultures also form holoclones, meroclones, and paraclones, and tumor cell holoclones have been hypothesized to harbor stem - like cells or
cancer stem cells.
Last year, Mandriota and collaborators demonstrated that in a
cancer mouse model, concentrations of aluminum in the amount of those measured in the human breast are able to transform
cultured mammary
epithelial cells, allowing them to form tumors and to metastasize.