Sentences with phrase «cyclin e1»

Au - Yeung G, Lang F, Azar WJ, Mitchell C, Jarman KE, Lackovic K, Aziz D, Cullinane C, Pearson RB, Mileshkin L, Rischin D, Karst AM, Drapkin R, Etemadmoghadam D, Bowtell DD.: Selective targeting of Cyclin E1 amplified high grade serous ovarian cancer by cyclin - dependent kinase 2 and AKT inhibition.

Differentiation is associated with a decrease in cyclin E1 and a concomitant elevation in D - type cyclins and cdk inhibitor transcripts [57], [60].

Undifferentiated ES cells are also characterized by elevated levels of transcripts encoding the G1 / S transition - promoting complex cyclin E1: Cdk2 and, by contrast, low levels of transcripts encoding D - type cyclins and Cdk4 / 6 inhibitors of the INK4 family (p15, p16, p18, p19; Figure 7).

26) Lockwood WW, Stack D, Morris T, Grehan D, O'Keane C, Cumiskey J, Lam WL, Squire JA, Thomas D, O'Sullivan M (2011) Cyclin E1 is amplified and over-expressed in osteosarcoma.

For instance, Cluster 1 contains genes such as cyclin A2, cyclin B1, cyclin E1, cyclin F, polymerase alpha 2, RNA polymerase II polypeptide H, and RNA polymerase III polypeptide G, whereas Cluster 3 genes include Nanog, Sox2, Pou5f1 (Oct4), Klf2, Zpf42 (Rex1) and Esrrb.